Recombinant Human Histone Deacetylase 6, FLAG-tagged
Cat.No. : | HDAC6-398H |
Product Overview : | Recombinanthuman HDAC6 was expressed in E. coli as the full length protein with anN-terminal FLAG tag. The molecular weight of the protein is 132 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | HDAC6-398H |
Description : | HDAC6is a histone deacetylase containig two HDAC catalytic domains. HDAC6 is anenzyme that in humans is encoded by the HDAC6 gene. Histones play a critical rolein transcriptional regulation, cell cycle progression, and developmentalevents. It contains an internal duplication of two catalytic domains whichappear to function independently of each other. |
Source : | E. coli |
Species : | Human |
Reconstitution : | 20 mM Tris-HCl (pH7.3), 300 mM KCl, 0.2 mM EDTA and 20%glycerol. |
Contents : | 10g recombinant HDAC6 protein, 0.5 g/l. |
Dilution of Protein : | RecombinantHDAC6 is supplied in solution and should be kept as a solution in ordertomaintain full activity. |
Application : | RecombinantHDAC6 is suitable for use in histone deacetylase assays. Arecommendedstarting point for the HDAC assay is 20-100 ng of recombinant proteinperreaction. |
Storage : | Recombinantproteins in solution are temperature sensitive and should be stored at-80°Cto prevent degradation. Avoid repeated freeze/thaw cycles and keep on icewhennot in storage. |
Gene Name : | HDAC6 histonedeacetylase 6 [ Homo sapiens ] |
Official Symbol : | HDAC6 |
Synonyms : | HDAC6;histone deacetylase 6; HD6; JM21; FLJ16239; EC 3.5.1.98; KIAA0901;OTTHUMP00000032398; OTTHUMP00000197663 |
Gene ID : | 10013 |
mRNA Refseq : | NM_006044 |
Protein Refseq : | NP_006035 |
MIM : | 300272 |
UniProt ID : | Q9UBN7 |
Chromosome Location : | Xp11.23 |
Pathway : | Cell cycle; NOTCH1 Intracellular DomainRegulates Transcription; Signal Transduction; Signaling by NOTCH; Signalingby NOTCH1; Signaling events mediated by HDAC Class I; Signaling eventsmediated by HDAC Class II; TNF-alpha/NF-kB Signaling Pathway |
Function : | Hsp90 protein binding; NAD-dependenthistone deacetylase activity (H3-K14 specific); NAD-dependent histonedeacetylase activity (H3-K9 specific); NAD-dependent histone deacetylaseactivity (H4-K16 specific); actin binding; alpha-tubulin binding;beta-catenin binding; beta-tubulin binding; dynein complex binding; enzymebinding; histone deacetylase activity; histone deacetylase activity (H3-K16specific); histone deacetylase binding; hydrolase activity; metal ion binding |
Products Types
◆ Recombinant Protein | ||
Hdac6-1104M | Recombinant Mouse Hdac6 Protein, MYC/DDK-tagged | +Inquiry |
HDAC6-4092M | Recombinant Mouse HDAC6 Protein, His (Fc)-Avi-tagged | +Inquiry |
HDAC6-313H | Active Recombinant Human HDAC6 Protein | +Inquiry |
HDAC6-1877R | Recombinant Rhesus Macaque HDAC6 Protein, His (Fc)-Avi-tagged | +Inquiry |
HDAC6-096H | Recombinant Human HDAC6 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
HDAC6-5603HCL | Recombinant Human HDAC6 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1028 | HDAC6 Activity Assay Kit (Fluorometric) | +Inquiry |
Kit-1742 | HDAC6 Fluorogenic Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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