"SAE1" Related Products

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Recombinant Human SUMO1 Activating Enzyme Subunit 1

Cat. No.: SAE1-61H
Product Overview: Recombinant human SAE1(aa1-347)produced in E. coli is a heterodimer that acts as the activatingenzyme for SUMO-1.
Description: Posttranslationalmodification of proteins by the addition of the small protein SUMO (seeSUMO1; MIM 601912), or sumoylation, regulates protein structure andintracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimerthat functions as a SUMO-activating enzyme for the sumoylation of proteins.
Source: E. coli
Species: Human
Concentration: 0.2mg/ml
Formulation: Liquid.In 50mM TRIS-HCl, pH 7.5, containing 1mM DTT and 200mM potassium chloride.
Storage: -80°C, LongTerm.
OfficialSymbol: SAE1
Gene Name: SAE1 SUMO1 activating enzymesubunit 1 [ Homo sapiens ]
Synonyms: SAE1; SUMO1 activatingenzyme subunit 1; SUMO-1 activating enzyme E1 N subunit; SUMO-1 activatingenzyme subunit 1; SUMO-activating enzyme subunit 1; activator of SUMO1;sentrin/SUMO-activating protein AOS1; ubiquitin-like 1-activating enzyme E1A;ubiquitin-like protein SUMO-1 activating enzyme; AOS1; FLJ3091; HSPC140
Gene ID: 10055
mRNA Refseq: NM_001145713
Protein Refseq: NP_001139185
MIM: 613294
UniProt ID: Q9UBE0
Chromosome Location: 19q13.32
Pathway: Ubiquitin mediated proteolysis
Function: ATP-dependent protein binding; contributes_to SUMO activatingenzyme activity; enzyme activator activity; ligase activity; protein heterodimerizationactivity; protein binding; ubiquitin activating enzyme activity

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