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Recombinant Human ELAVL1(1-100aa), GST-tagged

Cat.No. : ELAVL1-02H
Product Overview : Recombinant Human ELAVL1 partial ORF (1 a.a. - 100 a.a.) fused with GST-tag at N-terminal, was expressed in vitro wheat germ.
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Cat. No. : ELAVL1-02H
Description : ELAV-like protein 1 or HuR (human antigen R) is a protein that in humans is encoded by the ELAVL1 gene. The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It stabilizes mRNAs and thereby regulates gene expression.
Source : Wheat Germ
Species : Human
Predicted MolecularMass : 36.74 kDa
AminoAcid Sequence : MSNGYEDHMAEDCRGDIGRTNLIVN YLPQNMTQDELRSLFSSIGEVESAK LIRDKVAGHSLGYGFVNYVTAKDAE RAINTLNGLRLQSKTIKVSYARPSS
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Applications : ELISA; WB
Stability& Storage : Store at -80°C. Aliquot to avoid repeated freezing and thawing.
OfficialSymbol : ELAVL1
Gene Name : ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) [ Homo sapiens ]
Synonyms : ELAVL1; ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); HUR; Hua; MelG; ELAV1; ELAV-like protein 1; Hu antigen R; hu-antigen R; embryonic lethal, abnormal vision, drosophila, homolog-like 1
Gene ID : 1994
mRNA Refseq : NM_001419
Protein Refseq : NP_001410
MIM : 603466
UniProt ID : Q15717
Chromosome Location : 19p13.2
Pathway : Gene Expression; Regulation of mRNA Stability by Proteins that Bind AU-rich Elements; Stabilization of mRNA by HuR
Function : AU-rich element binding; RNA binding; mRNA binding; nucleotide binding; protein binding; tein kinase binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Is relationship between the ELAVL1 gene and the immune system? 04/28/2022

Studies have shown that the ELAVL1 gene may be involved in the regulation of the immune system, especially in the inflammatory response.

What is the localization of the ELAVL1 gene in cells? 01/19/2021

The protein encoded by the ELAVL1 gene is mainly located in the cytoplasm and nucleus.

What is the change in the expression level of ELAVL1 gene in tumors? 10/24/2020

In some tumors, the expression level of ELAVL1 gene may be increased or decreased, which is related to the occurrence and progression of tumors.

What is the effect of ELAVL1 gene on apoptosis? 04/21/2020

This gene may play an important role in the process of apoptosis, but its specific mechanism of action still needs further research.

How is the ELAVL1 gene involved in the differentiation of nerve cells? 02/10/2020

ELAVL1 is involved in the differentiation of nerve cells by binding to and stabilizing neuronal cell-specific microRNAs.

In which tissues and organs is the ELAVL1 gene expressed? 02/08/2020

This gene isexpressed in many tissues and organs, including the brain, heart, liver, muscles, etc.

Customer Reviews (3)

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Reviews
12/19/2022

    It is very pure and can be used with confidence.

    07/20/2021

      In enzymatic experiments, ELAVL1 was found to have high catalytic efficiency.

      06/11/2020

        In immunological experiments, it was found that ELAVL1 had good antigenicity and could induce target immune response.

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