Recombinant Human Troponin C Type 2 (fast)

• Cat.No.: TNNC2-6924H
• Product Overview: Recombinant human TNNC2 was expressed in E. coli and purified by using conventional chromatography. MW: 18.1 kDa.

Specification

• Description: TNNC2 is the central regulatory protein of striated muscle contraction, and modulates the Ca2+-activation characteristics of muscle fibers. Troponin has 3 subunits, Troponin I, Troponin T and Troponin C. Tn-I subunit inhibits actomyosin ATPase and Tn-T subunit binds tropomyosin and Tn-C, while Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments.
• Source: E. coli
• Species: Human
• Tag: N/A
• Form: Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 1mM DTT, 100mM NaCl, 10% glycerol.
• Molecular Mass: 18.1 kDa (160aa), confirmed by MALDI-TOF.
• Protein length: 1-160aa
• AA Sequence: MTDQQAEARS YLSEEMIAEF KAAFDMFDAD GGGDISVKEL GTVMRMLGQT PTKEELDAII EEVDEDGSGT IDFEEFLVMM VRQMKEDAKG KSEEELAECF RIFDRNADGY IDPEELAEIF RASGEHVTDE EIESLMKDGD KNNDGRIDFD EFLKMMEGVQ
• Purity: >95% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: TNNC2 troponin C type 2 (fast) [ Homo sapiens ]
• Official Symbol: TNNC2
• Synonyms: TNNC2; troponin C type 2 (fast); troponin C2, fast; troponin C, skeletal muscle
• Gene ID: 7125
• mRNA Refseq: NM_003279
• Protein Refseq: NP_003270
• MIM: 191039
• UniProt ID: P02585
• Chromosome Location: 20q12-q13.11
• Pathway: Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Muscle contraction, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem
• Function: contributes_to actin binding; calcium ion binding