Recombinant Human Betacellulin, His-tagged
Cat.No. : | BTC-869H |
Product Overview : | Recombinant human BTC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 11.3 kDa. |
- Specification
- Gene Information
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Description : | BTC (Betacellulin) is a member of the EGF family of growth factors and contains 1 EGF-like domain. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor. The effects of BTC are probably mediated by the EGF receptor and other related receptors. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 20% glycerol, 200mM NaCl. |
Molecular Mass : | 11.3 kDa (101aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher). |
Protein length : | 32-111aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MDGNSTRSPE TNGLLCGDPE ENCAATTTQS KRKGHFSRCP KQYKHYCIKG RCRFVVAEQT PSCVCDEGYI GARCERVDLF Y |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25mg/ml (determined by Bradford assay) |
Gene Name : | BTC betacellulin [ Homo sapiens ] |
Official Symbol : | BTC |
Synonyms : | BTC; betacellulin; probetacellulin; |
Gene ID : | 685 |
mRNA Refseq : | NM_001729 |
Protein Refseq : | NP_001720 |
MIM : | 600345 |
UniProt ID : | P35070 |
Chromosome Location : | 4q13-q21 |
Pathway : | ErbB receptor signaling network, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, conserved biosystem; ErbB4 signaling events, organism-specific biosystem; GRB2 events in ERBB2 signaling, organism-specific biosystem; Nuclear signaling by ERBB4, organism-specific biosystem; |
Function : | epidermal growth factor receptor binding; growth factor activity; |
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◆ Lysates | ||
BTC-2505MCL | Recombinant Mouse BTC cell lysate | +Inquiry |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (6)
Ask a questionYes, BTC protein is involved in both energy metabolism and fat metabolism, so it has some potential in the treatment of metabolic diseases.
This protein has a role in the development and function of the nervous system to control the differentiation and growth of neurons.
BTC protein can promote cell proliferation, pocket sac (D472250) and microvascular growth, etc., and plays an important role in wound healing and repair.
This protein plays a regulatory role in the pathogenesis and treatment mechanism of PTSD, and is one of the new targets for the treatment of Wolverine poisoning.
It is involved in the occurrence and process of osteoporosis, and related research has become an important breakthrough in the treatment of osteoporosis.
BTC is involved in the occurrence and process of organ transplant rejection and has become one of the targets for the treatment of transplant rejection.
Customer Reviews (3)
Write a reviewBecause of its high activity, few experiments were successful, reducing the number of our experiments.
High cost performance, affordable price, good experimental effect.
Excellent product, perfect for western-blot.
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