"BTC" Related Products

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Recombinant Human Betacellulin, His-tagged

Cat.No. : BTC-869H
Product Overview : Recombinant human BTC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 11.3 kDa.
Description : BTC (Betacellulin) is a member of the EGF family of growth factors and contains 1 EGF-like domain. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor. The effects of BTC are probably mediated by the EGF receptor and other related receptors.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 20% glycerol, 200mM NaCl.
Molecular Mass : 11.3 kDa (101aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher).
Protein length : 32-111aa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MDGNSTRSPE TNGLLCGDPE ENCAATTTQS KRKGHFSRCP KQYKHYCIKG RCRFVVAEQT PSCVCDEGYI GARCERVDLF Y
Purity : >90% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 0.25mg/ml (determined by Bradford assay)
Gene Name : BTC betacellulin [ Homo sapiens ]
Official Symbol : BTC
Synonyms : BTC; betacellulin; probetacellulin;
Gene ID : 685
mRNA Refseq : NM_001729
Protein Refseq : NP_001720
MIM : 600345
UniProt ID : P35070
Chromosome Location : 4q13-q21
Pathway : ErbB receptor signaling network, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, conserved biosystem; ErbB4 signaling events, organism-specific biosystem; GRB2 events in ERBB2 signaling, organism-specific biosystem; Nuclear signaling by ERBB4, organism-specific biosystem;
Function : epidermal growth factor receptor binding; growth factor activity;

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