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Recombinant Human Betacellulin, His-tagged

Cat.No. : BTC-869H
Product Overview : Recombinant human BTC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 11.3 kDa.
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  • Gene Information
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Description : BTC (Betacellulin) is a member of the EGF family of growth factors and contains 1 EGF-like domain. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor. The effects of BTC are probably mediated by the EGF receptor and other related receptors.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 20% glycerol, 200mM NaCl.
Molecular Mass : 11.3 kDa (101aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher).
Protein length : 32-111aa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MDGNSTRSPE TNGLLCGDPE ENCAATTTQS KRKGHFSRCP KQYKHYCIKG RCRFVVAEQT PSCVCDEGYI GARCERVDLF Y
Purity : >90% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 0.25mg/ml (determined by Bradford assay)
Gene Name : BTC betacellulin [ Homo sapiens ]
Official Symbol : BTC
Synonyms : BTC; betacellulin; probetacellulin;
Gene ID : 685
mRNA Refseq : NM_001729
Protein Refseq : NP_001720
MIM : 600345
UniProt ID : P35070
Chromosome Location : 4q13-q21
Pathway : ErbB receptor signaling network, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, conserved biosystem; ErbB4 signaling events, organism-specific biosystem; GRB2 events in ERBB2 signaling, organism-specific biosystem; Nuclear signaling by ERBB4, organism-specific biosystem;
Function : epidermal growth factor receptor binding; growth factor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Does BTC protein have potential in the treatment of metabolic diseases? 11/24/2022

Yes, BTC protein is involved in both energy metabolism and fat metabolism, so it has some potential in the treatment of metabolic diseases.

How about BTC protein have an effect on nervous system development and function? 10/27/2022

This protein has a role in the development and function of the nervous system to control the differentiation and growth of neurons.

What is the role of BTC protein in wound repair? 09/21/2021

BTC protein can promote cell proliferation, pocket sac (D472250) and microvascular growth, etc., and plays an important role in wound healing and repair.

Does BTC protein have a role in PTSD treatment? 05/20/2021

This protein plays a regulatory role in the pathogenesis and treatment mechanism of PTSD, and is one of the new targets for the treatment of Wolverine poisoning.

What is the role of BTC protein in osteoporosis? 10/03/2020

It is involved in the occurrence and process of osteoporosis, and related research has become an important breakthrough in the treatment of osteoporosis.

What is the role of BTC protein in organ transplant rejection? 04/14/2020

BTC is involved in the occurrence and process of organ transplant rejection and has become one of the targets for the treatment of transplant rejection.

Customer Reviews (3)

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Reviews
12/16/2022

    Because of its high activity, few experiments were successful, reducing the number of our experiments.

    08/08/2021

      High cost performance, affordable price, good experimental effect.

      01/30/2021

        Excellent product, perfect for western-blot.

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