Active Recombinant Human FK506 Binding Protein 1B, 12.6 KDa, His-tagged
Cat.No. : | FKBP1B-2500H |
Product Overview : | Recombinant human FKBP1B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. MW: 14.2 kDa. |
- Specification
- Gene Information
- Related Products
Description : | FKBP1B, also known as peptidyl-prolyl cis-trans isomerase FKBP1B, is a member of the immunophilin protein family which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 (tacrolimus) and rapamycin (sirolimus). It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT. |
Bio-activity : | Specific activity is >300 nmoles/min/mg, and is defined as the amount of enzyme that cleaves 1umole of suc-AAFP-pNA per minute at 25℃ in Tris-Hcl pH8.0 using chymotrypsin. |
Molecular Mass : | 14.2 kDa (130aa), confirmed by MALDI-TOF |
Protein length : | 1-108aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH RSMGVEIETI SPGDGRTFPK KGQTCVVHYT GMLQNGKKFD SSRDRNKPFK FRIGKQEVIK GFEEGAAQMS LGQRAKLTCT PDVAYGATGH PGVIPPNATL IFDVELLNLE |
Purity : | >90% by SDS-PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4℃ short term (1-2 weeks). For long term storage, aliquot and store at -20℃ or -70℃. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25 mg/ml (determined by Bradford assay) |
Gene Name : | FKBP1B FK506 binding protein 1B, 12.6 kDa [ Homo sapiens ] |
Official Symbol : | FKBP1B |
Synonyms : | FKBP1B; FK506 binding protein 1B, 12.6 kDa; FK506 binding protein 1B (12.6 kD) , FKBP1L; peptidyl-prolyl cis-trans isomerase FKBP1B; FKBP9; FKBP12.6; OTK4; PPIase; FKBP-1B; rotamase; FKBP-12.6; h-FKBP-12; calstabin 2; 12.6 kDa FKBP; PPIase FKBP1B; immunophilin FKBP12.6; FK506-binding protein 1B; FK506-binding protein 12.6; 12.6 kDa FK506-binding protein; FKBP1L; PKBP1L; |
Gene ID : | 2281 |
mRNA Refseq : | NM_004116 |
Protein Refseq : | NP_004107 |
MIM : | 600620 |
UniProt ID : | P68106 |
Chromosome Location : | 2p23.3 |
Function : | FK506 binding; isomerase activity; peptidyl-prolyl cis-trans isomerase activity; protein binding; receptor binding; contributes_to ryanodine-sensitive calcium-release channel activity; |
Products Types
◆ Recombinant Protein | ||
FKBP1B-2010R | Recombinant Rat FKBP1B Protein, His (Fc)-Avi-tagged | +Inquiry |
FKBP1B-001H | Recombinant Human FKBP1B Protein | +Inquiry |
FKBP1B-1541R | Recombinant Rhesus Macaque FKBP1B Protein, His (Fc)-Avi-tagged | +Inquiry |
FKBP1B-5252H | Recombinant Human FKBP1B Protein | +Inquiry |
Fkbp1b-3024M | Recombinant Mouse Fkbp1b Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
FKBP1B-6209HCL | Recombinant Human FKBP1B 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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