Recombinant Human Destrin (actin depolymerizing factor), His-tagged

• Cat.No.: DSTN-6844H
• Product Overview: Recombinant human DSTN protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Specification

• Description: DSTN is a member of the ADF/Cofilin/destrin superfamily that has the ability to rapidly depolymerize F-Actin in a stoichiometric manner. DSTN is a small phosphoinositide-sensitive actin-binding protein capable of depolymerizing actin-filaments in vitro.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT.
• Molecular Mass: 19.5 kDa (173aa) confirmed by MALDI-TOF
• Protein length: 1-165aa
• AA Sequence: MASGVQVADE VCRIFYDMKV RKCSTPEEIK KRKKAVIFCL SADKKCIIVE EGKEILVGDV GVTITDPFKH FVGMLPEKDC RYALYDASFE TKESRKEELM FFLWAPELAP LKSKMIYASS KDAIKKKFQG IKHECQANGP EDLNRACIAE KLGGSLIVAF EGCPVLEHHH HHH
• Purity: >95% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: DSTN destrin (actin depolymerizing factor) [ Homo sapiens ]
• Official Symbol: DSTN
• Synonyms: DSTN; destrin (actin depolymerizing factor); destrin; ACTDP; ADF; actin-depolymerizing factor; bA462D18.2 (destrin (actin depolymerizing factor ADF) (ACTDP)); bA462D18.2
• Gene ID: 11034
• mRNA Refseq: NM_001011546
• Protein Refseq: NP_001011546
• MIM: 609114
• UniProt ID: P60981
• Chromosome Location: 20p12.1
• Function: actin binding