Recombinant Human Heat Shock 10kDa Protein 1 (chaperonin 10)
Cat.No. : | HSPE1-6930H |
Product Overview : | Recombinant human HSPE1 was expressed in E. coli and purified by using conventional chromatography techniques. MW: 10 KDa. |
- Specification
- Gene Information
- Related Products
Description : | HSPE1 is a member of the highly conserved group of molecular chaperons, which are necessary for efficient folding of many proteins in normal and stress conditions and have been implicated in several human diseases. HSPE1 is the ~10kD mammalian equivalent to GroES of E. coli. The function of Hsp10 is to bind Hsp60 (also known as chaperonin-60), in the presence of ATP, thereby promoting a conformational change in Hsp60 and enclosing the protein substrate within the complex. ATP hydrolysis by Hsp60 destabilizes the Hsp60/ HSPE1 complex, allowing it to dissociate and release the substrate protein. |
Source : | E. coli |
Species : | Human |
Tag : | N/A |
Form : | Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 50 mM NaCl |
Molecular Mass : | 10 kDa (102 aa), confirmed by MALDI-TOF |
Protein length : | 1-102aa |
AA Sequence : | MAGQAFRKFL PLFDRVLVER SAAETVTKGG IMLPEKSQGK VLQATVVAVG SGSKGKGGEI QPVSVKVGDK VLLPEYGGTK VVLDDKDYFL FRDGDILGKY VD |
Endotoxin : | < 1.0 eu per 1 μg of protein (determined by lal |
Purity : | >95% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | HSPE1 heat shock 10kDa protein 1 (chaperonin 10) [ Homo sapiens ] |
Official Symbol : | HSPE1 |
Synonyms : | HSPE1; heat shock 10kDa protein 1 (chaperonin 10); heat shock 10kD protein 1 (chaperonin 10); 10 kDa heat shock protein, mitochondrial; CPN10; GROES; chaperonin 10; 10 kDa chaperonin; early-pregnancy factor; EPF; HSP10; |
Gene ID : | 3336 |
mRNA Refseq : | NM_002157 |
Protein Refseq : | NP_002148 |
MIM : | 600141 |
UniProt ID : | P61604 |
Chromosome Location : | 2q33.1 |
Function : | ATP binding; chaperone binding; chaperone binding; protein binding; unfolded protein binding; |
Products Types
◆ Recombinant Protein | ||
Hspe1-1193M | Recombinant Mouse Hspe1 Protein, MYC/DDK-tagged | +Inquiry |
HSPE1-042H | Recombinant Human HSPE1 Protein | +Inquiry |
HSPE1-1993R | Recombinant Rhesus Macaque HSPE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
HSPE1-5263H | Recombinant Human HSPE1 Protein, GST-tagged | +Inquiry |
HSPE1-5043H | Recombinant Human Heat Shock 10 KDa Protein 1 (Chaperonin 10) | +Inquiry |
◆ Lysates | ||
HSPE1-5339HCL | Recombinant Human HSPE1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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