"HSPE1" Related Products

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Recombinant Human Heat Shock 10kDa Protein 1 (chaperonin 10)

Cat.No.: HSPE1-6930H
Product Overview: Recombinant human HSPE1 was expressed in E. coli and purified by using conventional chromatography techniques. MW: 10 KDa.
Description: HSPE1 is a member of the highly conserved group of molecular chaperons, which are necessary for efficient folding of many proteins in normal and stress conditions and have been implicated in several human diseases. HSPE1 is the ~10kD mammalian equivalent to GroES of E. coli. The function of Hsp10 is to bind Hsp60 (also known as chaperonin-60), in the presence of ATP, thereby promoting a conformational change in Hsp60 and enclosing the protein substrate within the complex. ATP hydrolysis by Hsp60 destabilizes the Hsp60/ HSPE1 complex, allowing it to dissociate and release the substrate protein.
Source: E. coli
Species: Human
Tag: N/A
Form: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 50 mM NaCl
Molecular Mass: 10 kDa (102 aa), confirmed by MALDI-TOF
Protein length: 1-102aa
AA Sequence: MAGQAFRKFL PLFDRVLVER SAAETVTKGG IMLPEKSQGK VLQATVVAVG SGSKGKGGEI QPVSVKVGDK VLLPEYGGTK VVLDDKDYFL FRDGDILGKY VD
Endotoxin: < 1.0 eu per 1 μg of protein (determined by lal
Purity: >95% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 1 mg/ml (determined by Bradford assay)
Gene Name: HSPE1 heat shock 10kDa protein 1 (chaperonin 10) [ Homo sapiens ]
Official Symbol: HSPE1
Synonyms: HSPE1; heat shock 10kDa protein 1 (chaperonin 10); heat shock 10kD protein 1 (chaperonin 10); 10 kDa heat shock protein, mitochondrial; CPN10; GROES; chaperonin 10; 10 kDa chaperonin; early-pregnancy factor; EPF; HSP10;
Gene ID: 3336
mRNA Refseq: NM_002157
Protein Refseq: NP_002148
MIM: 600141
UniProt ID: P61604
Chromosome Location: 2q33.1
Function: ATP binding; chaperone binding; chaperone binding; protein binding; unfolded protein binding;

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