"SNAP25" Related Products

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Recombinant Human Synaptosomal-Associated Protein, 25kDa

Cat.No.: SNAP25-6928H
Product Overview: Recombinant SNAP25 protein was expressed in E. coli and purified by using conventional chromatography techniques. MW: 23 kDa.
Description: SNAP25 is an essential component of the core complex that mediates presynaptic vesicle trafficking. Thus, SNAP-25 is directly involved in the release of neurotransmitters and this protein exists as two alternative isoforms, SNAP25A and SNAP25B which differ by 9 amino acids in central portion of these proteins.
Source: E. coli
Species: Human
Tag: N/A
Form: Liquid in 25mM Tris pH 7.5, 1mM DTT, 2mM EDTA, 10% glycerol
Molecular Mass: 23 kDa (206 aa), confirmed by MALDI-TOF.
Protein length: 1-206aa
AA Sequence: MAEDADMRNE LEEMQRRADQ LADESLESTR RMLQLVEESK DAGIRTLVML DEQGEQLERI EEGMDQINKD MKEAEKNLTD LGKFCGLCVC PCNKLKSSDA YKKAWGNNQD GVVASQPARV VDEREQMAIS GGFIRRVTND ARENEMDENL EQVSGIIGNL RHMALDMGNE IDTQNRQIDR IMEKADSNKT RIDEANQRAT KMLGSG
Purity: >90% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 1 mg/ml (determined by Bradford assay)
Gene Name: SNAP25 synaptosomal-associated protein, 25kDa [ Homo sapiens ]
Official Symbol: SNAP25
Synonyms: SNAP25; synaptosomal-associated protein, 25kDa; SNAP, synaptosomal associated protein, 25kD; synaptosomal-associated protein 25; bA416N4.2; dJ1068F16.2; resistance to inhibitors of cholinesterase 4 homolog; RIC 4; RIC4; SEC9; SNAP 25; SUP; super protein; SNAP; RIC-4; SNAP-25; FLJ23079;
Gene ID: 6616
mRNA Refseq: NM_003081
Protein Refseq: NP_003072
MIM: 600322
UniProt ID: P60880
Chromosome Location: 20p12-p11.2
Pathway: Acetylcholine Neurotransmitter Release Cycle, organism-specific biosystem; BoNT Light Chain Types A, C1, E cleave SNAP-25, organism-specific biosystem; Botulinum neurotoxicity, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Dopamine Neurotransmitter Release Cycle, organism-specific biosystem; Effects of Botulinum toxin, organism-specific biosystem;
Function: SNARE binding; myosin binding; protein N-terminus binding; protein binding; protein domain specific binding; syntaxin-1 binding; voltage-gated potassium channel activity;

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