Active Recombinant Human KAT2A, GST-tagged
Cat.No. : | KAT2A-1392H |
Product Overview : | Recombinant human KAT2A (GCN5) (323-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | KAT2A (K (lysine) acetyltransferase 2A) is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator which functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner. KAT2A control chromosome stability by coordinating the ATR checkpoint and double-strand break processing with autophagy. KAT2A acetyltransferases have homologous sequences and enzymatic activities which are important for recognition of nucleosomal substrates. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 22 nmol/min/mg |
Molecular Mass : | ~82 kDa |
Protein length : | 323 aa-end |
Purity : | >85% |
Applications : | Acetyltransferase Assay |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | KAT2A K(lysine) acetyltransferase 2A [ Homo sapiens ] |
Official Symbol : | KAT2A |
Synonyms : | KAT2A; K(lysine) acetyltransferase 2A; GCN5 general control of amino acid synthesis 5 like 2 (yeast) , GCN5L2; histone acetyltransferase KAT2A; GCN5; PCAF b; STAF97; hsGCN5; lysine acetyltransferase 2A; histone acetyltransferase GCN5; general control of amino acid synthesis protein 5-like 2; General control of amino acid synthesis, yeast, homolog-like 2; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2; hGCN5; GCN5L2; PCAF-b; MGC102791; |
Gene ID : | 2648 |
mRNA Refseq : | NM_021078 |
Protein Refseq : | NP_066564 |
MIM : | 602301 |
UniProt ID : | Q92830 |
Chromosome Location : | 17q12-q21 |
Pathway : | C-MYC pathway, organism-specific biosystem; E2F transcription factor network, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; |
Function : | H3 histone acetyltransferase activity; chromatin binding; histone acetyltransferase activity; contributes_to histone acetyltransferase activity; histone acetyltransferase activity (H4-K12 specific); histone deacetylase binding; protein binding; transcription coactivator activity; transferase activity; |
Products Types
◆ Recombinant Protein | ||
KAT2A-058H | Recombinant Human KAT2A Protein, His-tagged | +Inquiry |
KAT2A-005H | Recombinant Human KAT2A Protein, His-tagged | +Inquiry |
KAT2A-2352H | Recombinant Human KAT2A Protein, His-tagged | +Inquiry |
KAT2A-18H | Recombinant Human KAT2A Protein, GST-tagged | +Inquiry |
KAT2A-29886TH | Recombinant Human KAT2A, His-tagged | +Inquiry |
◆ Lysates | ||
KAT2A-290HCL | Recombinant Human KAT2A HEK293T cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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