Recombinant Human HFE, His-tagged
Cat.No. : | HFE-7087H |
Product Overview : | Recombinant human HFE protein, fused to His-tag at N-terminus, was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | HFE, also known as HLA-H, belongs to the MHC class I family. This protein contains 1 Ig-like C1-type (immunoglobulin-like) domain. HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta-2 microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor (TFR) with transferrin. It binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea,10% glycerol |
Molecular Mass : | 35.7kDa (308aa) |
Protein length : | 23-306aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMRLLRSH SLHYLFMGAS EQDLGLSLFE ALGYVDDQLF VFYDHESRRV EPRTPWVSSR ISSQMWLQLS QSLKGWDHMF TVDFWTIMEN HNHSKESHTL QVILGCEMQE DNSTEGYWKY GYDGQDHLEF CPDTLDWRAA EPRAWPTKLE WERHKIRARQ NRAYLERDCP AQLQQLLELG RGVLDQQVPP LVKVTHHVTS SVTTLRCRAL NYYPQNITMK WLKDKQPMDA KEFEPKDVLP NGDGTYQGWI TLAVPPGEEQ RYTCQVEHPG LDQPLIVIWE PSPSGTLV |
Purity : | >85% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml |
Gene Name : | HFE hemochromatosis [ Homo sapiens ] |
Official Symbol : | HFE |
Synonyms : | HFE; hemochromatosis; hereditary hemochromatosis protein; high Fe; HLA H; MHC class I-like protein HFE; hereditary hemochromatosis protein HLA-H; HH; HFE1; HLA-H; MVCD7; TFQTL2; MGC103790; MGC:150812; dJ221C16.10.1; IMAGE:40125754; |
Gene ID : | 3077 |
mRNA Refseq : | NM_000410 |
Protein Refseq : | NP_000401 |
MIM : | 613609 |
UniProt ID : | Q30201 |
Chromosome Location : | 6p21.3 |
Function : | protein binding; |
Products Types
◆ Recombinant Protein | ||
HFE-1895R | Recombinant Rhesus Macaque HFE Protein, His (Fc)-Avi-tagged | +Inquiry |
HFE-4144M | Recombinant Mouse HFE Protein, His (Fc)-Avi-tagged | +Inquiry |
HFE-4721H | Recombinant Human HFE Protein, GST-tagged | +Inquiry |
Hfe-1120M | Recombinant Mouse Hfe Protein, MYC/DDK-tagged | +Inquiry |
HFE-258H | Recombinant Human HFE Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
HFE-5572HCL | Recombinant Human HFE 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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