Recombinant Human FASLG, His-tagged

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Recombinant Human FASLG, His-tagged

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Cat.No. : FASLG-7108H
Product Overview : Recombinant human FASLG protein, fused to His-tag at N-terminus, was expressed in E.coli.
Description : Fas ligand, also known as FASLG, belongs to the tumor necrosis factor family and is the ligand for FAS. Both are transmembrane proteins. Interaction of FAS with this ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Defects in FASLG may be related to some cases of systemic lupus erythematosus (SLE).
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Molecular Mass : 9.6kDa (173aa)
Protein length : 130-281aa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MQIGHPSPPP EKKELRKVAH LTGKSNSRSM PLEWEDTYGI VLLSGVKYKK GGLVINETGL YFVYSKVYFR GQSCNNLPLS HKVYMRNSKY PQDLVMMEGK MMSYCTTGQM WARSSYLGAV FNLTSADHLY VNVSELSLVN FEESQTFFGL YKL
Purity : >90% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/ml
Gene Name : FASLG Fas ligand (TNF superfamily, member 6) [ Homo sapiens ]
Official Symbol : FASLG
Synonyms : FASLG; Fas ligand (TNF superfamily, member 6); APT1LG1, TNFSF6, tumor necrosis factor (ligand) superfamily, member 6; tumor necrosis factor ligand superfamily member 6; CD178; FasL; APTL; CD95 ligand; fas antigen ligand; apoptosis antigen ligand; apoptosis (APO-1) antigen ligand 1; tumor necrosis factor (ligand) superfamily, member 6; FASL; CD95L; CD95-L; TNFSF6; APT1LG1;
Gene ID : 356
mRNA Refseq : NM_000639
Protein Refseq : NP_000630
MIM : 134638
UniProt ID : P48023
Chromosome Location : 1q23
Pathway : Activation of Pro-Caspase 8, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem;
Function : cytokine activity; protein binding; receptor binding; tumor necrosis factor receptor binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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