Recombinant Human MYC, His-tagged


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Recombinant Human MYC, His-tagged

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Cat. No. : MYC-1029H
Product Overview : Recombinant humanMYC full-length protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by nickel NTA affinity chromatography.
Description : c-Myc is a conserved cellular gene. The gene product is anuclear-bound 62,000 molecular weight phosphoprotein (p62c-myc). The nuclear p62c-myc content increased with DNA synthesis in tumors and mucosa.
Source : E. coli.
Formulation : 50 μg recombinant protein in Renaturation buffer ( 20 mM Tris-HCl , 150 mM NaCl, 1 mM EDTA, 5 mM Glutathione,0.5 mM GSSH and 10% Glycerol), lyophilized.Reconstitute the contents using sterile water no less than 100 μg/ml.
Molecular weight : 62 kDa
Purity : > 90% by SDS PAGE and coomassie blue staining.
Usage : It can be used for WB, ELISA.
Storage : Upon receiving, the proteins can be stored at 4°C. After reconstitution,store the working aliquots at -80°C. Avoid repeated freeze and thaw.
Gene Name : MYC v-myc myelocytomatosis viral oncogene homolog (avian) [ Homo sapiens ]
Synonyms : MYC; v-myc myelocytomatosis viral oncogene homolog (avian); MRTL; c-Myc; bHLHe39; avian myelocytomatosis viral oncogene homolog; v-myc avian myelocytomatosis viral oncogene homolog; myc-related translation/localization regulatory factor
Gene ID : 4609
mRNA Refseq : NM_002467
Protein Refseq : NP_002458
MIM : 190080
UniProt ID : P01106
Chromosome Location : 8q24
Pathway : Acute myeloid leukemia; Bladder cancer; Chronic myeloid leukemia; Colorectal cancer; ErbB signaling pathway; Colorectal cancer; Jak-STAT signaling pathway; MAPK signaling pathway; Pathways in cancer; Small cell lung cancer; Small cell lung cancer; Thyroid cancer; Wnt signaling pathway
Function : protein binding; transcription factor activity

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