Recombinant Human MYC Protein, MYC/DDK-tagged, C13 and N15-labeled
Cat.No. : | MYC-060H |
Product Overview : | MYC MS Standard C13 and N15-labeled recombinant protein (NP_002458) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 50.5 kDa |
AA Sequence : | Tags(s)LDFFRVVENQQPPATMPLNVSFTNR NYDLDYDSVQPYFYCDEEENFYQQQ QQSELQPPAPSEDIWKKFELLPTPP LSPSRRSGLCSPSYVAVTPFSLRGD NDGGGGSFSTADQLEMVTELLGGDM VNQSFICDPDDETFIKNIIIQDCMW SGFSAAAKLVSEKLASYQAARKDSG SPNPARGHSVCSTSSLYLQDLSAAA SECIDPSVVFPYPLNDSSSPKSCAS QDSSAFSPSSDSLLSSTESSPQGSP EPLVLHEETPPTTSSDSEEEQEDEE EIDVVSVEKRQAPGKRSESGSPSAG GHSKPPHSPLVLKRCHVSTHQHNYA APPSTRKDYPAAKRVKLDSVRVLRQ ISNNRKCTSPRSSDTEENVKRRTHN VLERQRRNELKRSFFALRDQIPELE NNEKAPKVVILKKATAYILSVQAEE QKLISEEDLLRKRREQLKHKLEQLR NSCATRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | MYC MYC proto-oncogene, bHLH transcription factor [ Homo sapiens (human) ] |
Official Symbol : | MYC |
Synonyms : | MYC; MYC proto-oncogene, bHLH transcription factor; bHLHe39; c-Myc; MRTL; MYCC; myc proto-oncogene protein; avian myelocytomatosis viral oncogene homolog; class E basic helix-loop-helix protein 39; myc-related translation/localization regulatory factor; proto-oncogene c-Myc; transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog; |
Gene ID : | 4609 |
mRNA Refseq : | NM_002467 |
Protein Refseq : | NP_002458 |
MIM : | 190080 |
UniProt ID : | P01106 |
Products Types
◆ Recombinant Protein | ||
MYC-3498R | Recombinant Rat MYC Protein, His (Fc)-Avi-tagged | +Inquiry |
MYC-32H | Recombinant Active Human c-Myc Protein (1-454) | +Inquiry |
MYC-5787H | Recombinant Human MYC Protein, GST-tagged | +Inquiry |
Myc-4239M | Recombinant Mouse Myc Protein, Myc/DDK-tagged | +Inquiry |
MYC-2735R | Recombinant Rhesus Macaque MYC Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
MYC-4039HCL | Recombinant Human MYC 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1785 | Myc Reporter Kit (Myc Signaling Pathway) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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