"VPS24" Related Products

Recombinant Human VPS24, His-tagged

Cat. No.: VPS24-3561H
Product Overview: Recombinant human VPS24 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography (1-222aa).
Description: VPS24, also known as Charged multivesicular body protein 3(CHMP3), belongs to the vacuolar sorting protein family and function as chromatin modifying proteins. It associates directly with CHMP2 and CHMP4 for the disassembly of ESCRT-III complex in an ATP-dependent manner. During HIV-1 infection, the virus uses the ESCRT-III complex to mediate budding and exocytosis of viral proteins. Overexpression of VPS24 strongly inhibits HIV-1 release.
Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl, 1mM DTT
Molecular Weight: 27.2 kDa (242aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Purity: > 90% by SDS - PAGE
Concentration: 1.0 mg/ml (determined by Bradford assay)
Sequences Of Amino Acids: GSSHHHHHH SSGLVPRGSH MGLFGKTQEK PPKELVNEWS LKIRKEMRVV DRQIRDIQRE EEKVKRSVKD AAKKGQKDVC IVLAKEMIRS RKAVSKLYAS KAHMNSVLMG MKNQLAVLRV AGSLQKSTEV MKAMQSLVKI PEIQATMREL SKEMMKAGII EEMLEDTFES MDDQEEMEEE AEMEIDRILF EITAGALGKA PSKVTDALPE PEPPGAMAAS EDEEEEEEAL EAMQSRLATL RS.
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: VPS24 vacuolar protein sorting 24 homolog (S. cerevisiae) [ Homo sapiens ]
Official Symbol: VPS24
Synonyms: VPS24; vacuolar protein sorting 24 homolog (S. cerevisiae); NEDF; CHMP3; CGI-149; FLJ38114; charged multivesicular body protein 3; 25.1 protein; OTTHUMP00000203324; OTTHUMP00000203325; OTT- HUMP00000203326; CHMP family, member 3; chro- matin-modifying protein 3; neuroendocrine differentiation factor; vacuolar protein sorting-associated protein 24; hVps24; vacuolar protein sorting 24 (yeast); Neur- oendocrine differentiation factor; Vacuolar protein sorting-associated protein 24
Gene ID: 51652
mRNA Refseq: NM_016079
Protein Refseq: NP_057163
MIM: 610052
UniProt ID: Q9Y3E7
Chromosome Location: 2p11.2
Function: protein binding

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