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Recombinant Human FGF19 protein(Phe27-Lys216)

Cat.No. : FGF19-7336H
Product Overview : Recombinant Human FGF19 protein(O95750-1)(Phe27-Lys216) was expressed in E. coli.
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  • Gene Information
  • Related Products
similar : FGF19
Alias : FGF19; fibroblast growth factor 19; FGF-19;
Source : E. coli
Species : Human
Conjugate : N/A
Tag : N/A
Protein length : Phe27-Lys216
Form : Lyophilized from sterile 50mM Tris, 300mM NaCl, pH 8.5. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
MolecularMass : The recombinant human FGF19 consists of 191 amino acids and predicts a molecular mass of 21.4 KDa. It migrates as an approximately 23 KDa band in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 90 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
GeneName : FGF19 fibroblast growth factor 19 [ Homo sapiens ]
GeneNameWeblink : 9965
OfficialSymbol : FGF19
OfficialSymbolWeblink : 9965
GeneID : 9965
GeneIDWeblink : 9965
mRNARefseq : NM_005117
mRNARefseqWeblink : NM_005117.2
ProteinRefseqWeblink : NP_005108.1
MIMWeblink : 603891
UniProtID : O95750
UniProtIDWeblink : O95750
Synonyms : FGF19; fibroblast growth factor 19; FGF-19;
MIM : 603891
Synonyms : FGF19; fibroblast growth factor 19; FGF-19;
MIM : 603891

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is FGF19 gene expression regulated, and what factors influence its secretion and activity in various tissues? 09/12/2021

FGF19 expression is regulated by bile acids and other factors. Its secretion and activity are influenced by nutrient availability, signaling pathways, and interactions with bile acid receptors.

Can you discuss the potential therapeutic applications of targeting FGF19 in metabolic disorders, and what challenges exist in developing such interventions? 05/20/2020

Targeting FGF19 holds therapeutic potential for metabolic disorders. Challenges include achieving tissue-specific effects and understanding the long-term consequences of manipulating FGF19 signaling.

Can you explain the role of FGF19 in the enterohepatic circulation of bile acids and its implications for metabolic health? 04/05/2019

FGF19 regulates bile acid synthesis in the liver and influences the enterohepatic circulation, impacting metabolic health by modulating lipid and glucose metabolism.

What is the role of FGF19 in the regulation of gut hormone secretion, and how does this contribute to its effects on metabolic processes? 02/02/2019

FGF19 influences gut hormone secretion, including the release of glucagon-like peptide-1 (GLP-1). This regulation contributes to its metabolic effects, such as enhanced insulin sensitivity and reduced food intake.

What is the significance of FGF19 in metabolic diseases, and how does dysregulation contribute to conditions like obesity and non-alcoholic fatty liver disease (NAFLD)? 12/29/2018

Dysregulation of FGF19 is implicated in metabolic diseases, including obesity and NAFLD. Altered FGF19 signaling may contribute to aberrant bile acid and lipid metabolism in these conditions.

Customer Reviews (3)

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Reviews
01/14/2022

    Top-notch protein quality! It's our go-to for reliable and reproducible results.

    09/08/2020

      This product simplifies our research. It's a reliable tool that we can count on.

      05/11/2018

        If you're in the lab, you need this product. It streamlines processes and is a lab necessity.

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