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Recombinant Human SIGLEC5 protein, Fc-tagged

Cat.No. : SIGLEC5-7330H
Product Overview : Recombinant Human SIGLEC5 (Glu17-Thr434) protein was fused to human IgG1 Fc tag at C-terminus and expressed in human 293 cells (HEK293).
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Description : Sialic acid-binding Ig-like lectin 5 (SIGLEC5) is also known as CD33 antigen-like 2 (CD33L2), Obesity-binding protein 2 (OB-BP2), CD antigen CD170, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5/CD170 is expressed by monocytic/myeloid lineage cells. SIGLEC-5/CD33-L2 binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Source : HEK293
Species : Human
Tag : human IgG1 Fc
Predicted N Terminal : Glu17
Form : Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 73.0 kDa. The protein migrates as 90-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein length : Glu17-Thr434
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : SIGLEC5
Official Symbol : SIGLEC5
Synonyms : SIGLEC5; sialic acid binding Ig-like lectin 5; CD33L2; sialic acid-binding Ig-like lectin 5; CD170; OB BP2; SIGLEC 5; CD33 antigen-like 2; OB-binding protein 2; obesity-binding protein 2; sialic acid-binding immunoglobulin-like lectin 5; OBBP2; OB-BP2; SIGLEC-5
Gene ID : 8778
mRNA Refseq : NM_003830
Protein Refseq : NP_003821
MIM : 604200
UniProt ID : O15389

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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