Rat Anti-IL5 Monoclonal Antibody

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Rat Anti-IL5 Monoclonal Antibody

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Cat.No. : DMABT-H19267
Product Overview : Rat Anti-IL5 Monoclonal Antibody
Antigen Description : IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. TheKFT2-40E20antibody can neutralize the bioactivity of natural or recombinant IL-5.
Target : IL5
Immunogen : COS-expressed, recombinant human IL-5
Host : Rat
Isotype : IgG2a, kappa
species : Human
Clone : KFT2-40E20
Conjugation : LEAF
Applications : ELISA,ELISPOT,Neut,IHC,WB
Preparation : The LEAF (Low Endotoxin, Azide-Free) antibody was Purified by affinity chromatography.
Usage recommendation : Each lot of this antibody is quality control tested by ELISA assay. For use as an ELISPOT capture antibody, a concentration range of 4-8 μg/ml is recommended. For ELISA capture applications, a concentration range of 1-4 μg/ml is recommended. To obtain a linear standard curve, serial dilutions of IL-5 recombinant protein ranging from 500 to 4 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.
Concentration : 1.0 mg/ml
Storage : The antibody solution should be stored undiluted at 4 °C. This LEAF solution contains no preservative; handle under aseptic conditions.
Size : 500 μg
Gene Name : IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Homo sapiens ]
Official Symbol : IL5
Synonyms : IL5; interleukin 5 (colony-stimulating factor, eosinophil); interleukin-5; B cell differentiation factor I; EDF; eosinophil differentiation factor; IL 5; interleukin 5; T cell replacing factor; TRF; T-cell replacing factor; B-cell differentiation factor I; IL-5;
Gene ID : 3567
mRNA Refseq : NM_000879
Protein Refseq : NP_000870
MIM : 147850
UniProt ID : P05113
Chromosome Location : 5q23-q31
Pathway : Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem;
Function : cytokine activity; growth factor activity; interleukin-5 receptor binding; protein binding;

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