Rat Anti-IL5 Monoclonal Antibody

• Cat.No.: DMABT-H19267
• Product Overview: Rat Anti-IL5 Monoclonal Antibody

Specification

• Antigen Description: IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. TheKFT2-40E20antibody can neutralize the bioactivity of natural or recombinant IL-5.
• Target: IL5
• Immunogen: COS-expressed, recombinant human IL-5
• Host: Rat
• Isotype: IgG2a, kappa
• species: Human
• Clone: KFT2-40E20
• Conjugation: LEAF
• Applications: ELISA,ELISPOT,Neut,IHC,WB
• Preparation: The LEAF (Low Endotoxin, Azide-Free) antibody was Purified by affinity chromatography.
• Usage recommendation: Each lot of this antibody is quality control tested by ELISA assay. For use as an ELISPOT capture antibody, a concentration range of 4-8 μg/ml is recommended. For ELISA capture applications, a concentration range of 1-4 μg/ml is recommended. To obtain a linear standard curve, serial dilutions of IL-5 recombinant protein ranging from 500 to 4 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.
• Concentration: 1.0 mg/ml
• Storage: The antibody solution should be stored undiluted at 4 °C. This LEAF solution contains no preservative; handle under aseptic conditions.
• Size: 500 μg

Gene Information

• Gene Name: IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Homo sapiens ]
• Official Symbol: IL5
• Synonyms: IL5; interleukin 5 (colony-stimulating factor, eosinophil); interleukin-5; B cell differentiation factor I; EDF; eosinophil differentiation factor; IL 5; interleukin 5; T cell replacing factor; TRF; T-cell replacing factor; B-cell differentiation factor I; IL-5
• Gene ID: 3567
• mRNA Refseq: NM_000879
• Protein Refseq: NP_000870
• MIM: 147850
• UniProt ID: P05113
• Chromosome Location: 5q23-q31
• Pathway: Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem
• Function: cytokine activity; growth factor activity; interleukin-5 receptor binding; protein binding