Recombinant Mouse Interleukin 5

• Cat.No.: Il5-224M

Specification

• Cat. No.: Il5-224M
• Description: Interleukin 5 or IL-5 is an interleukin produced by T helper-2 cells and mast cells. Its functions are to stimulate B cell growth and increase immunoglobulin secretion. It is the main factor that promotes the terminal differentiation of eosinophil progenitors and enhances the effector capacity of mature eosinophils. IL-5 is a TH2 cytokine which is part of the hematopoietic family. Unlike other members of this cytokine family in its active form, this glycoprotein is a homodimer. IL-5 expression is regulated by several transcription factors including GATA-3.
• Source: Sf 21 Insect Cells.
• Molecular Weight: The predicted molecular weight of Recombinant Mouse IL-5 is Mr 32-34 kDa.
• State Of Matter: Solution.
• Purity: >97% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Storage And Stability: -20°C to -70°C.

Gene Information

• Gene Name: Il5 interleukin 5 [ Mus musculus ]
• Synonyms: Il5; interleukin 5; Il-5; OTTMUSP00000005818
• Gene ID: 16191
• mRNA Refseq: NM_010558
• Protein Refseq: NP_034688
• UniProt ID: P04401
• Chromosome Location: 11 A5/B1; 11 29.2 cM
• Pathway: Allograft rejection; Autoimmune thyroid disease; Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway; Hematopoietic cell lineage; Jak-STAT signaling pathway; T cell receptor signaling pathway
• Function: cytokine activity; growth factor activity; interleukin-5 receptor binding