Mouse Anti-LTA Monoclonal Antibody

• Cat.No.: DMABT-H19264
• Product Overview: Mouse Anti-LTA Monoclonal Antibody

Specification

• Species: Human
• Source: Mouse
• Tag: Non
• Antigen Description: Tumor necrosis factor-beta (TNF-beta), also known as lymphotoxin-alpha (LT-alpha) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. TNF-beta possesses a signal peptide sequence and is a secreted protein; however, TNF-beta is also present on the surface of activated T, B and LAK cells as a complex with LT-beta. Bioactive TNF-beta exists as a homotrimer.
• Target: LTA
• Immunogen: E.coli expressed, recombinant human TNF-beta
• Isotype: IgG1, kappa
• species: Human
• Clone: 460-92-22
• Conjugation: Biotin
• Applications: ELISA,ELISPOT
• Preparation: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
• Usage recommendation: Each lot of this antibody is quality control tested by ELISA assay. For ELISA detection applications, a concentration range of 0.25-1.0 μg/ml is recommended. For immunofluorescent staining, the suggested use of this reagent is ≤0.25 μg per 106cells in 100 μl volume. It is recommended that the reagent be titrated for optimal performance for each application.
• Concentration: 0.5 mg/ml
• Storage: The antibody solution should be stored undiluted at 4 °C.Do not freeze.
• Size: 500 μg

Gene Information

• Gene Name: LTA lymphotoxin alpha (TNF superfamily, member 1) [ Homo sapiens ]
• Official Symbol: LTA
• Synonyms: LTA; lymphotoxin alpha (TNF superfamily, member 1); TNFB; lymphotoxin-alpha; LT; TNFSF1; LT-alpha; TNF-beta; tumor necrosis factor beta; tumor necrosis factor ligand superfamily member 1
• Gene ID: 4049
• mRNA Refseq: NM_000595
• Protein Refseq: NP_000586
• MIM: 153440
• UniProt ID: P01374
• Chromosome Location: 6p21.3
• Pathway: Apoptosis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem
• Function: cytokine activity; receptor binding; tumor necrosis factor receptor binding