"RAMP3" Related Products

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Recombinant Human RAMP3, His-tagged

Cat.No.: RAMP3-7526H
Product Overview: Recombinant human RAMP3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Antigen Description: RAMP3, also known as receptor activity modifying protein 3, is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). It is required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR can function as either a calcitonin gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
Molecular Mass: 13.0 kDa(116aa) confirmed by MALDI-TOF
Protein length: 24-118aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MRAGGCNETG MLERLPLCGK AFADMMGKVD VWKWCNLSEF IVYYESFTNC TEMEANVVGC YWPNPLAQGF ITGIHRQFFS NCTVDRVHLE DPPDEV
Purity: >90% as determined by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
Concentration: 0.5 mg/ml
Gene Name: RAMP3 receptor (G protein-coupled) activity modifying protein 3 [ Homo sapiens ]
Official Symbol: RAMP3
Synonyms: RAMP3; receptor (G protein-coupled) activity modifying protein 3; receptor (calcitonin) activity modifying protein 3 , receptor activity modifying protein 3; receptor activity-modifying protein 3; CRLR activity-modifying protein 3; receptor activity modifying protein 3; receptor-activity-modifying protein 3; receptor (calcitonin) activity modifying protein 3; calcitonin receptor-like receptor activity modifying protein 3; calcitonin-receptor-like receptor activity-modifying protein 3;
Gene ID: 10268
mRNA Refseq: NM_005856
Protein Refseq: NP_005847
MIM: 605155
UniProt ID: O60896
Chromosome Location: 7p13-p12
Pathway: Calcitonin-like ligand receptors, organism-specific biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
Function: coreceptor activity; protein binding; protein transporter activity; receptor activity;

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