"TUBB3" Related Products

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Recombinant Human TUBB3, His-tagged

Cat.No.: TUBB3-7552H
Product Overview: Recombinant human TUBB3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Antigen Description: Tubulin, beta 3 class III, also known as TUBB3, is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB3 plays a critical role in proper axon guidance and mantainance.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl,10% glycerol, 1mM DTT
Molecular Mass: 52.8 kDa (473aa)
Protein length: 1-450aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMREIVHI QAGQCGNQIG AKFWEVISDE HGIDPSGNYV GDSDLQLERI SVYYNEASSH KYVPRAILVD LEPGTMDSVR SGAFGHLFRP DNFIFGQSGA GNNWAKGHYT EGAELVDSVL DVVRKECENC DCLQGFQLTH SLGGGTGSGM GTLLISKVRE EYPDRIMNTF SVVPSPKVSD TVVEPYNATL SIHQLVENTD ETYCIDNEAL YDICFRTLKL ATPTYGDLNH LVSATMSGVT TSLRFPGQLN ADLRKLAVNM VPFPRLHFFM PGFAPLTARG SQQYRALTVP ELTQQMFDAK NMMAACDPRH GRYLTVATVF RGRMSMKEVD EQMLAIQSKN SSYFVEWIPN NVKVAVCDIP PRGLKMSSTF IGNSTAIQEL FKRISEQFTA MFRRKAFLHW YTGEGMDEME FTEAESNMND LVSEYQQYQD ATAEEEGEMY EDDEEESEAQ GPK
Purity: >90% as determined by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
Concentration: 0.25 mg/ml
Gene Name: TUBB3 tubulin, beta 3 class III [ Homo sapiens ]
Official Symbol: TUBB3
Synonyms: TUBB3; tubulin, beta 3 class III; tubulin, beta 3; tubulin beta-3 chain; beta 4; class III beta tubulin; tubulin beta-III; tubulin beta-4 chain; class III beta-tubulin; CDCBM; TUBB4; beta-4; CFEOM3A;
Gene ID: 10381
mRNA Refseq: NM_001197181
Protein Refseq: NP_001184110
MIM: 602661
UniProt ID: Q13509
Chromosome Location: 16q24.3
Pathway: Chaperonin-mediated protein folding, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cooperation of Prefoldin and TriC/CCTin actin and tubulin folding, organism-specific biosystem; Diurnally regulated genes with circadian orthologs, organism-specific biosystem; Formation of tubulin folding intermediates by CCT/TriC, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem;
Function: GTP binding; GTPase activity; nucleotide binding; structural molecule activity;

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