"Ccl2" Related Products

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Recombinant Rabbit Chemokine (C-C Motif) Ligand 2

Cat. No. : Ccl2-283R
Product Overview : Recombinant Rat MCP-1 produced in E.Coli is a non-glycosylated, Polypeptide chain containing 125 amino acids and having a molecular mass of 14092 Dalton.
Description : Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1) and small inducible cytokine A2. CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury, infection, and inflammation.
Species : Rabbit
Source : E.coli
Form : Lyophilized with no additive.
Purity : Purity Greater than 95% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Bio-activity : MCP-1 is fully biologically active when compared to standard. The specific activity as determined by the ability of Rat MCP-1 to chemoattract human peripheral blood at 10-100ng/ml.
Physical Appearance : Sterile Filtered white lyophilized (freeze-dried) powder.
Solubility : It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Purity Greater than 95% as determined by : Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Protein Content determined by : UV spectroscopy at 280 nm. Analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Endotoxin Level : Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Amino acid sequence : QPDAVNAPLT CCYSFTGKMI PMSRLENYKR ITSSRCPKEA VVFVTKLKRE ICADPNKEW-V QKYIRKLDQN QVRSETTVFY KIASTLRTSA PLNVNLT-HKS EANASTLFST TTSSTSVEVT SMTE
Storage : Lyophilized product is very stable at -20 degrees. Reconstituted material should be aliquoted and frozen at -20. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.
PDB rendering based on 1dok. :

Gene Name : Ccl2 chemokine (C-C motif) ligand 2 [ Rattus norvegicus ]
Official Symbol : Ccl2
Synonyms : Ccl2; chemokine (C-C motif) ligand 2; MCP-1; Scya2; Sigje;monocyte chemotactic protein 1; small inducible cytokine A2; monocyte chemoattractant protein-1; Small inducible gene JE
Gene ID : 24770
mRNA Refseq : NM_031530
Protein Refseq : NP_113718
UniProt ID : P14844
Chromosome Location : 10q26
Pathway : Chemokine signaling pathway; Cytokine-cytokine receptor interaction
Function : CCR2 chemokine receptor binding; G-protein-coupled receptor binding; heparin binding; protein binding

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