"CCL4" Related Products

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Recombinant Human Chemokine (C-C Motif) Ligand 4

Cat. No.: CCL4-294H
Product Overview: Recombinant Human MIP-1 produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 69 amino acids and having a molecular mass of 7620 Dalton.
Description: Chemokine (C-C motif) ligand 4, also known as CCL4, is a protein which in humans is encoded by the CCL4 gene.
Species: Human
Source: E.coli
Form: Lyopohilized with no additives.
Purity: Purity Greater than 98% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Bio-activity: Human MIP-1 is fully biologically active when compared to standard. The Activity is calculated by the ability to chemoattract human blood monocytes using a concentration of 2.5-15 ng/ml.
Physical Appearance: Sterile Filtered white lyophilized (freeze-dried) powder.
Solubility: Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg"s/ml, which can be further diluted into other aqueous solutions.
Purity Greater than 98% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Protein Content determined by: UV spectroscopy at 280 nm. Analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Endotoxin Level: Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Amino acid sequence: APMGSDPPTA CCFSYTARKL PHNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESWVQ EYVYDLELN
Storage: Lyophilized product is very stable at -20 degrees. Reconstituted material should be aliquoted and frozen at -20. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.
Gene Name: CCL4 chemokine (C-C motif) ligand 4 [ Homo sapiens ]
Official Symbol: CCL4
Synonyms: ACT2; G-26; LAG1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta; CCL4; chemokine C-C motif ligand 4; CC chemokine ligand 4; secreted protein G-26; lymphocyte-activation gene 1; small inducible cytokine A4 (homologous to mouse Mip-1b); Macrophage inflammatory protein 1-beta; Short name=MIP-1-beta; MIP-1-beta(1-69); T-cell activation protein 2; Short name=ACT-2; PAT 744; Protein H400; SIS-gamma; Lymphocyte activation gene 1 protein; Short name=LAG-1; HC21; T-lymphocyte-secreted protein; MIP-1-beta(3-69); LAG1; MGC104418; MGC126025; MGC126026
Gene ID: 6351
mRNA Refseq: NM_002984
Protein Refseq: NP_002975
MIM: 182284
UniProt ID: P13236
Chromosome Location: 17q12
Pathway: Chemokine signaling pathway; Cytokine-cytokine receptor interaction; Toll-like receptor signaling pathway
Function: chemokine activity; receptor signaling protein; tyrosine kinase activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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