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Recombinant Human HAO1, His tagged

Cat.No. : HAO1-3795H
Product Overview : Recombinant Human HAO1 (NP_060015.1) (Leu 2-Ile 370), fused with a polyhistide tag at the N-terminus, was produced in E. coli.
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Source : E. coli
Species : Human
Tag : His
Form : Lyophilized from sterile 20mM Tirs, 500mM NaCl, 10% glycerol, pH 8.0
Molecular Mass : The recombinant human HAO1 consisting of 376 amino acids and migrates as an 42 kDa band in SDS-PAGE under reducing conditions as predicted.
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Stability : Samples are stable for up to twelve months from date of receipt at -70oC.
Storage : Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : HAO1 hydroxyacid oxidase (glycolate oxidase) 1 [ Homo sapiens ]
Official Symbol : HAO1
Gene ID : 54363
mRNA Refseq : NM_017545
Protein Refseq : NP_060015
MIM : 605023
UniProt ID : Q9UJM8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How is HAO1 implicated in metabolic disorders? 02/14/2022

Dysregulation of HAO1 is linked to metabolic disorders and fatty liver disease.

Are there existing or potential therapeutic strategies targeting HAO1? 09/04/2021

Therapeutic approaches may include modulation of HAO1 activity or expression.

How does HAO1 contribute to fatty acid metabolism? 08/15/2020

It oxidizes specific fatty acids, contributing to their breakdown.

What are the key biological functions of HAO1? 07/14/2020

HAO1 is involved in peroxisomal fatty acid oxidation, crucial for lipid metabolism.

What are the potential consequences of HAO1 overexpression? 06/15/2020

HAO1 overexpression may lead to oxidative stress and liver dysfunction.

What role does HAO1 play in liver function? 01/01/2019

HAO1 supports liver function by participating in lipid catabolism.

How is HAO1 activity regulated in cells? 10/13/2018

Cellular regulation of HAO1 involves transcriptional and post-translational mechanisms.

Customer Reviews (3)

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05/09/2022

    Worked well in experiments.

    11/28/2020

      Great for academic research.

      01/28/2020

        Very satisfied, will buy again.

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