"Igf1" Related Products

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Recombinant Mouse Insulin-Like Growth Factor 1

Cat. No.: Igf1-570M
Product Overview: Recombinant mouse IGF-1 produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 70 amino acids and having a molecular mass of 7600 Dalton.
Description: A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on Somatotropin. It is believed to be mainly active in adults in contrast to Insulin like Growth Factor 2, which is a major fetal growth factor.
Species: Mouse
Source: E.coli
Form: Recombinant Mouse IGF-1 was lyophilized with no additives.
Purity: Purity Greater than 98% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Bio-activity: Recombinant Mouse IGF-I is fully biologically active when compared to standards. The ED50, calculated by the dose-dependent proliferation of MCF-7 cells, is less than 1.0 ng/ml.
Physical Appearance: Sterile Filtered white lyophilized (freeze-dried) powder.
Solubility: Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mgμs/ml, which can be further diluted into other aqueous solutions.
Purity Greater than 98% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Protein Content determined by: UV spectroscopy at 280 nm. Analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Endotoxin Level: Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Amino acid sequence: GPETLCGAEL VDALQFVCGP RGFYFNKPTG YGSSIRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPTKAA
Storage: Lyophilized product is very stable at -20 degrees. Reconstituted material should be aliquoted and frozen at -20. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.
Gene Name: Igf1 insulin-like growth factor 1 [ Mus musculus ]
Official Symbol: Igf1
Synonyms: Igf1; insulin-like growth factor 1; Igf-1; Igf-I; C730016P09Rik; somatomedin; MGI:96432; MGD-MRK-11226; MGD-MRK-11228; MGI:2444166; IBP1; IGF-IA; IGF-IB; IGF1A; IGFI; MGF; Somatomedin-C; Mechano growth factor; insulin-like growth factor1 (somatomedin C)
Gene ID: 16000
mRNA Refseq: NM_001111274
Protein Refseq: NP_001104744
UniProt ID: P05017
Chromosome Location: 10 C1; 10 48.0 cM
Pathway: Focal adhesion; p53 signaling pathway lioma; Hypertrophic cardiomyopathy (HCM); mTOR signaling pathway; Long-term depression; Melanoma; Pathways in cancer; Prostate cancer
Function: Growth factor activity; Hormone activity; Insulin-like growth factor receptor binding; Protein binding

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