Recombinant Human Resistin RETN-305H

Recombinant Human Resistin


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Recombinant Human Resistin

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Cat. No. : RETN-305H
Product Overview : Resistin, a product of the RSTN gene, is a peptide hormone belonging to the class of cysteine-rich secreted proteins which is termed the RELM family, and is also described as ADSF (Adipose Tissue- Specific Secretory Factor) and FIZZ3 (Found in Inflammatory Zone).
Description : Resistin also known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) is a cysteine-rich protein that in humans is encoded by the RETN gene.
Species : Human
Source : E.coli
Form : Sterile filtered and lyophilized from 0.1% TFA.
Purity : Purity Greater than 95% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Bio-activity : Determined by its ability to stimulate lipolysis in human adipocytes.
Physical Appearance : Sterile Filtered white lyophilized (freeze-dried) powder.
Solubility : Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mgμs/ml, which can be further diluted into other aqueous solutions.
Purity Greater than 95% as determined by : Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Protein Content determined by : UV spectroscopy at 280 nm. Analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Endotoxin Level : Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Storage : Lyophilized product is very stable at -20 degrees. Reconstituted material should be aliquoted and frozen at -20. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.
Crystallographicstructure of a hexamer of mouse resistin (rainbow colored, N-terminus = blue,C-terminus = red). :

Gene Name : RETN resistin [ Homo sapiens ]
Official Symbol : RETN
Synonyms : RETN; Cysteine-rich secreted protein; FIZZ3; Adipose tissue-specific secretory factor (ADSF); C/EBP-epsilon; regulated myeloid-sepcific secreted cysteine-rich protein; Cysteine-rich secreted protein A12-alpha-like-2; ADSF; MGC126603; MGC126609; RETN1; XCP1; resistin; MGC126609; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1; Adipose tissue-specific secretory factor; C/EBP-epsilon regulated myeloid-specific secreted; cysteine-rich protein precursor 1; cysteine-rich protein; Cysteine-rich secreted protein FIZZ3; found in inflammatory zone 3
Gene ID : 56729
mRNA Refseq : NM_020415
Protein Refseq : NP_065148
MIM : 605565
UniProt ID : Q9HD89
Chromosome Location : 19p13.2
Function : hormone activity

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