"GSTP1" Related Products

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Recombinant Human GSTP1, His-tagged

Cat. No. : GSTP1-1086H
Product Overview : Human GSTP1 (NP_000843, 1 a.a. - 210 a.a.) full-length recombinant protein with His tag expressed in Escherichia coli.
Description : GSTP1 is a glutathione S-transferase that belongs to the pi class. This enzyme acts by catalyzing the reaction of glutathione with an acceptor molecule to form an S-substituted glutathione (S=sulfur). The reactions utilizing glutathione contribute the transformation of a wide variety of electrophiles, including reactive products of lipid, protein, carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress.
Sequence : MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMPP YTVVYFPVRG RCAALRMLLA DQGQSWKEEV VTVETWQEGS LKASCLYGQL PKFQDGDLTL YQSNTILRHL GRTLGLYGKD QQEAALVDMV NDGVEDLRCK YISLIYTNYE AGKDDYVKAL PGQLKPFETL LSQNQGGKTF IVGDQISFAD YNLLDLLLIH EVLAPGCLDA FPLLSAYVGR LSARPKLKAF LASPEYVNLP INGNGKQ
Theoretical MW (kDa) : 27.6
Form : Liquid
Preparation Method : E. coli expression system
Purity : > 95% by SDS-PAGE
Endotoxin Level : < 1.0 EU per 1 microgram of protein (determined by LAL method)
Activity : Specific activity is < 6.5 units/mg, and is defined as the amount of enzyme that conjugate 1.0 umole of 1-chloro-2,4-dinitrobenzene (CDNB) with reduced glutathione per minute at pH 6.5 at 25°C.
Application : SDS-PAGE
Storage Buffer : In 20 mM Tris-HCl, 1 mM EDTA, 0.1 mM PMSF, pH 7.0 (30% glycerol)
Storage : Store at 4°C for 1-2 weeks. For long term storage store at -20°C or -80°C. Aliquot to avoid repeated freezing and thawing.
Unitprot ID : P09211
Gene Name : GSTP1 glutathione S-transferase pi 1 [ Homo sapiens ]
Official Symbol : GSTP1
Synonyms : GSTP1; glutathione S-transferase pi 1; PI; DFN7; GST3; FAEES3; deafness, X-linked 7; fatty acid ethyl ester synthase III; EC 2.5.1.18; 3` partial; GST class-pi; GSTP1-1; OTTHUMP00000174659; glutathione transferase
Gene ID : 2950
mRNA Refseq : NM_000852
Protein Refseq : NP_000843
MIM : 134660
Chromosome Location : 11q13-qter
Pathway : Drug metabolism - cytochrome P450; Glutathione metabolism; Metabolism of xenobiotics by cytochrome P450; Pathways in cancer; Prostate cancer; Biological oxidations
Function : glutathione transferase activity; protein binding; transferase activity

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