"GSTP1" Related Products

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Recombinant Human GSTP1, His-tagged

Cat. No.: GSTP1-1086H
Product Overview: Human GSTP1 (NP_000843, 1 a.a. - 210 a.a.) full-length recombinant protein with His tag expressed in Escherichia coli.
Description: GSTP1 is a glutathione S-transferase that belongs to the pi class. This enzyme acts by catalyzing the reaction of glutathione with an acceptor molecule to form an S-substituted glutathione (S=sulfur). The reactions utilizing glutathione contribute the transformation of a wide variety of electrophiles, including reactive products of lipid, protein, carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress.
Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMPP YTVVYFPVRG RCAALRMLLA DQGQSWKEEV VTVETWQEGS LKASCLYGQL PKFQDGDLTL YQSNTILRHL GRTLGLYGKD QQEAALVDMV NDGVEDLRCK YISLIYTNYE AGKDDYVKAL PGQLKPFETL LSQNQGGKTF IVGDQISFAD YNLLDLLLIH EVLAPGCLDA FPLLSAYVGR LSARPKLKAF LASPEYVNLP INGNGKQ
Theoretical MW (kDa): 27.6
Form: Liquid
Preparation Method: E. coli expression system
Purity: > 95% by SDS-PAGE
Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method)
Activity: Specific activity is < 6.5 units/mg, and is defined as the amount of enzyme that conjugate 1.0 umole of 1-chloro-2,4-dinitrobenzene (CDNB) with reduced glutathione per minute at pH 6.5 at 25°C.
Application: SDS-PAGE
Storage Buffer: In 20 mM Tris-HCl, 1 mM EDTA, 0.1 mM PMSF, pH 7.0 (30% glycerol)
Storage: Store at 4°C for 1-2 weeks. For long term storage store at -20°C or -80°C. Aliquot to avoid repeated freezing and thawing.
Unitprot ID: P09211
Gene Name: GSTP1 glutathione S-transferase pi 1 [ Homo sapiens ]
Official Symbol: GSTP1
Synonyms: GSTP1; glutathione S-transferase pi 1; PI; DFN7; GST3; FAEES3; deafness, X-linked 7; fatty acid ethyl ester synthase III; EC 2.5.1.18; 3` partial; GST class-pi; GSTP1-1; OTTHUMP00000174659; glutathione transferase
Gene ID: 2950
mRNA Refseq: NM_000852
Protein Refseq: NP_000843
MIM: 134660
Chromosome Location: 11q13-qter
Pathway: Drug metabolism - cytochrome P450; Glutathione metabolism; Metabolism of xenobiotics by cytochrome P450; Pathways in cancer; Prostate cancer; Biological oxidations
Function: glutathione transferase activity; protein binding; transferase activity

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