Recombinant Human Heat Shock 27kDa Protein 1 HSPB1-4923H

Recombinant Human Heat Shock 27kDa Protein 1


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Recombinant Human Heat Shock 27kDa Protein 1

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Cat. No. : HSPB1-4923H
Product Overview : Recombinant Human HSPB1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 205 amino acids and have a molecular weight of 22.7 kDa. The protein was purified by proprietary chromatographic techniques.
Description : HSPB1 is a protein that in humans is encoded by the HSPB1 gene. HSPB1 is a chaperone of the sHsp (small heat shock protein) group among ubiquitin, α-crystallin, Hsp20 and others. The common functions of sHsps are chaperone activity, thermotolerance, inhibition of apoptosis, regulation of cell development, and cell differentiation. They also take part in signal transduction.
Biological Activity : Immunoreactivity is confirmed by reaction with monoclonal mouse antibodies against HSPB1.
Molecular Weight : 22.7 kDa
Source : E. coli
Species : Human
Form : 1 mg/ml solution containing 20 mM Hepes (pH 7.5), 1 mM DTT and 100 mM KCl.
Appearance : Liquid
Endotoxin Level : <0.1 ng/μg
Purity : >98% by SDS-PAGE and HPLC analyses
Storage : Store at 4 °C for 2-7 days and store at -20 °C for future use. For long-term storage, it is recommended to add a carrier protein (0.1% HAS or BSA). Aviod freeze-thaw cycle.
Pathways : Amoebiasis; Destabilization of mRNA by AUF1 (hnRNP D0); FAS pathway and Stress induction of HSP regulation; IL-3 Signaling Pathway; IL-6 Signaling Pathway; MAPK signaling pathway; Metabolism of RNA; Metabolism of mRNA; Regulation of mRNA Stability by Proteins that Bind AU-rich Elements; Signaling events mediated by VEGFR1 and VEGFR2; TNF-alpha/NF-kB Signaling Pathway; VEGF signaling pathway
Gene Name : HSPB1 heat shock 27kDa protein 1 [ Homo sapiens ]
Official Symbol : HSPB1
Synonyms : HSPB1; heat shock 27kDa protein 1; CMT2F; HMN2B; HSP27; HSP28; Hsp25; SRP27; HS.76067; DKFZp586P1322; HSPB1; OTTHUMP00000024846; heat shock protein beta-1; HSPB1 heat shock 27kDa protein 1; 28 kDa heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; Stress-responsive protein 27; heat shock 27kD protein 1; heat shock 27kDa protein 1; heat shock protein beta-1
Gene ID : 3315
mRNA Refseq : NM_001540
Protein Refseq : NP_001531
MIM : 602195
UniProt ID : P04792
Chromosome Location : 7q11.23
Function : protein binding; protein kinase C delta binding; protein kinase C inhibitor activity; ubiquitin binding

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