Recombinant Human PIK3R1 Protein, His-tagged
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Cat.No. : | PIK3R1-4934H |
Product Overview : | Recombinant full-length human PI3K (p85alpha) was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. |
Description : | Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. |
Source : | Insect cells |
Species : | Human |
Tag : | His |
Molecular Mass : | ~86 kDa |
Purity : | > 95% |
Applications : | Kinase Assay, Western Blot |
Stability : | One year at -70 centigrade from date of shipment. |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.2 μg/μL |
Storage Buffer : | Recombinate protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0,1mM PMSF, 0,25mM DTT, 25% glycerol. |
Purity : |
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Gene Name : | PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 [ Homo sapiens (human) ] |
Official Symbol : | PIK3R1 |
Synonyms : | p85; AGM7; GRB1; IMD36; p85-ALPHA; PIK3R1; phosphoinositide-3-kinase regulatory subunit 1; phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase subunit p85-alpha; PI3K regulatory subunit alpha; phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha); phosphatidylinositol 3-kinase-associated p-85 alpha; phosphoinositide-3-kinase regulatory subunit alpha; phosphoinositide-3-kinase, regulatory subunit 1 (alpha); ptdIns-3-kinase regulatory subunit alpha |
Gene ID : | 5295 |
mRNA Refseq : | NM_181523 |
Protein Refseq : | NP_852664 |
MIM : | 171833 |
UniProt ID : | P27986 |
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◆ Lysates
PIK3R1-3185HCL | Recombinant Human PIK3R1 293 Cell Lysate | +Inquiry |
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PIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3C2BPIK3R4PIK3AP1PIK3C2APIK3C2GPIK3R3PIK3R5PIK3C3PIK3IP1PIK3R6
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