"EIF2AK4" Related Products

Recombinant Human Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4, GST-tagged

Cat. No.: EIF2AK4-1011H
Product Overview: Recombinant human EIF2AK4 (192-1024) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: EIF2AK4 or eukaryotic translation initiation factor 2 alpha kinase 4 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 to downregulate protein synthesis in response to varied cellular stresses. The EIF2AK4 eIF2-alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid.
Applications: Kinase Assay; Western Blot
Molecular Weight: 132 kDa
Expression System: Sf9 insect cells using baculovirus
Species: Human
Form: Recombinant protein stored in 50 mM Tris-HCl, ph 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol.
Specific Activity: 14 nmol/min/mg
Purity: > 95 %
Concentration: 0.1 ug/ul
Sequences: 192-1024
Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways: Hepatitis C; Herpes simplex infection; Influenza A; Measles; Protein processing in endoplasmic reticulum
Gene Name: EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 [ Homo sapiens ]
Official Symbol: EIF2AK4
Synonyms: EIF2AK4; eukaryotic translation initiation factor 2 alpha kinase 4; GCN2; KIAA1338; eukaryotic translation initiation factor 2-alpha kinase 4; GCN2-like protein; GCN2 eIF2alpha kinase; NP_001013725.2; EC 2.7.11.1
Gene ID: 440275
mRNA Refseq: NM_001013703
Protein Refseq: NP_001013725
MIM: 609280
UniProt ID: Q9P2K8
Chromosome Location: 15q15.1
Function: ATP binding; aminoacyl-tRNA ligase activity; nucleotide binding; protein homodimerization activity; protein serine/threonine kinase activity

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