Recombinant Human EGF Protein

• Cat.No.: EGF-04H
• Product Overview: Recombinant Human EGF Protein was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Description: This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
• Form: Lyophilized powder, with no additives.
• Molecular Mass: 6,200 Da
• Endotoxin: < 0.3ng/µg (0.3IEU/µg) determined by LAL test.
• Purity: >95% as determined by SDS-PAGE and SEC-HPLC.
• Storage: Store below -18 degree. Aliquot to avoid repeated freeze-thaw cycles.
• Publications:
  Engineering of a Bispecific Nanofitin with Immune Checkpoint Inhibitory Activity Conditioned by the Cross-Arm Binding to EGFR and PDL1 (2023)

Gene Information

• Gene Name: EGF epidermal growth factor [ Homo sapiens (human) ]
• Official Symbol: EGF
• Synonyms: URG; HOMG4
• Gene ID: 1950
• mRNA Refseq: NM_001963.6
• Protein Refseq: NP_001954.2
• MIM: 131530
• UniProt ID: P01133