"HDAC8" Related Products

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Recombinant Human Histone Deacetylase 8, His-tagged

Cat. No. : HDAC8-1595H
Product Overview : Full-length recombinant human HDAC8 was expressed by baculovirus in Sf9 insect cells using a C-terminal His tag.
Description : HDAC8 or Histone deacetylase 8 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. The protein encoded by this gene belongs to class I of the histone deacetylase family that catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors.
Applications : HDAC Assay; Western Blot
Molecular Weight : 47 kDa
Expression System : Sf9 insect cells using baculovirus
Species : Human
Form : Recombinant protein stored in 50 mM MOPS, PH 7.0, 300 mM NaCI, 150 mM imidazole, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Purity : >90%
Concentration : 0.05 ug/ul
Specific Activity : 1400 RLU/min/ng
Sequences : Full length
Storage : Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways : Signaling events mediated by HDAC Class I; Signaling events mediated by HDAC Class I
Gene Name : HDAC8 histone deacetylase 8 [ Homo sapiens ]
Official Symbol : HDAC8
Synonyms : HDAC8; histone deacetylase 8; HD8; RPD3; CDA07; HDACL1; histone deacetylase 8; OTTHUMP00000023539; OTTHUMP00000023540; OTTHUMP00000023541; OTTHUMP00000023542; OTTHUMP00000023543; OTTHUMP00000023544; OTTHUMP00000023545; OTTHUMP00000023546; OTTHUMP00000023549; histone deacetylase-like 1
Gene ID : 55869
mRNA Refseq : NM_001166418
Protein Refseq : NP_001159890
MIM : 300269
UniProt ID : Q9BY41
Chromosome Location : Xq13
Function : NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); histone deacetylase activity (H3-K16 specific); hydrolase activity; transcription factor binding; metal ion binding; histone deacetylase activity

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