"MKNK1" Related Products

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Recombinant Human MAP Kinase Interacting Serine/Threonine Kinase 1, GST-tagged

Cat. No. : MKNK1-1061H
Product Overview : Recombinant full-length human MKNK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description : MKNK1 (MAP kinase-interacting kinase 2) is a MAP kinase interacting serine/threonine kinase 1 that isolated by a novel expression screening method for identifying the protein kinase substrates. MKNK1 expressed in all tissues with the highest level of expression in skeletal muscle.
Applications : Kinase Assay; Western Blot
Molecular Weight : 92 kDa
Expression System : Sf9 insect cells using baculovirus
Species : Human
Form : Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Specific Activity : 20 nmol/min/mg
Purity : > 85%
Concentration : 0.1 ug/ul
Sequences : full-length
Storage : Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
PDB rendering basedon 2hw6. :

Gene Name : MKNK1 MAP kinase interacting serine/threonine kinase 1 [ Homo sapiens ]
Official Symbol : MKNK1
Synonyms : MKNK1; MAP kinase interacting serine/threonine kinase 1; MNK1; MKNK1; MAP kinase interacting kinase 1; EC 2.7.11.1; Mnk1; OTTHUMP00000009674; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1
Gene ID : 8569
mRNA Refseq : NM_001135553
Protein Refseq : NP_001129025
MIM : 606724
UniProt ID : Q9BUB5
Chromosome Location : 1p33
Pathway : Insulin signaling pathway; MAPK signaling pathway;IL-2 Signaling Pathway; Signaling mediated by p38-alpha and p38-beta; p38 MAPK Signaling Pathway
Function : ATP binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity

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