"PDGFB" Related Products


Recombinant Human Platelet-Derived Growth Factor-BB

Cat. No. : PDGFB-20H
Product Overview : Platelet-Derived Growth Factor-BB produced inE. colihas a molecular mass of 27KD.
Description : Platelet-Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF which is composed of a dimer of two chains termed the A chain and B chain, can be present as AA or BB homodimers or as an AB heterodimer. Recombinant human PDGF-BB is a24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids). Human recombinant platelet-derived growth factor is expressed inE. coli.
Purity : ≥95% as determined by SDS-PAGE.
PI : 9.39 by Isoelectricfocusing
concentration : 1 mg/ml by BCA
Component : Platelet-Derived Growth Factor-BB, PBS buffer, pH 7.4
Endotoxin : less than 10EU/mg as determined by LAL method
Storage Buffer : Liquid. In PBS Buffer.
Storagee : At 4°C for 6 months and -80°C for 2 years
PDBrendering based on 1pdg.Available structures:1pdg :

Gene Name : PDGFB
Synonyms : FLJ12858; PDGF2; SIS; SSV; c-sis; Becaplermin; PDGF-2; SIS; SSV; becaplermin; c-sis; HUMANES PDGF-B GEN AUS PGEM2-PDGF-B, FLANKIERT VON 5"-ECORI UND3"-HINDIII RESTRIKTIONSSCHNITTSTELLEN;PDGFB_HUMAN;PDGF B-chain; PDGF, B chain; PDGF-B VORLAEUFERSEQUENZ; Platelet-derived growth factor B chain precursor; Platelet-derived growth factor beta polypeptide; Platelet-derived growth factor, beta polypeptide (oncogene SIS); oncogene SIS ; platelet-derived growth factor 2; platelet-derived growth factor beta; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog); platelet-derived growth factor, B chain; v-sis platelet-derived growth factor beta polypeptide (simian sarcomaviral oncogene homolog); PDGFB
Gene ID : 5155
mRNA Refseq : NM_002608
Protein Refseq : NP_002599
MIM : 190040
UniProt ID : P01127
Chromosome Location : 22q12.3-q13.1; 22q13.1
Pathway : Cytokine-cytokine receptor interaction, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma.
Function : cell surface binding, growth factor activity, platelet-derived growth factor binding, platelet-derived growth factor receptor binding, protein binding, protein heterodimerization activity, protein homodimerization activity.

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