"STK38" Related Products

Recombinant Human Serine/Threonine Kinase 38, GST-tagged

Cat. No.: STK38-1106H
Product Overview: Full-length recombinant human STK38 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: STK38 is a serine/threonine kinase in the subgroup of the AGC kinase family that is regulated by Mob proteins. Fas and TNFα receptor stimulation activates human STK38 by promoting phosphorylation at the hydrophobic motif. STK38 acts as a novel pro-apoptotic kinase, and is a key member of the RASSF1A/MST1 signaling cascade. STK38 is crucial for the fidelity of mitotic chromosome alignment in mammalian cells. STK38 is incorporated into the HIV-1 particles and is cleared by the HIV-1 protease. STK38-driven centrosome duplication requires Cdk2 activity, and Cdk2-induced centrosome amplification is affected upon reduction of STK38 activity.
Applications: Kinase Assay; Western Blot
Molecular Weight: 81 kDa
Expression System: Sf9 insect cells using baculovirus
Species: Human
Form: Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol.
Specific Activity: 4 nmol/min/mg
Purity: > 70 %
Concentration: 0.1 ug/ul
Sequences: Full-length
Storage: Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: STK38 serine/threonine kinase 38 [ Homo sapiens ]
Official Symbol: STK38
Synonyms: STK38; serine/threonine kinase 38; NDR; NDR1; Nuclear Dbf2-related kinase 1; NDR1 protein kinase; serine/threonine-protein kinase 38; serine threonine protein kinase; nuclear Dbf2-related 1; EC 2.7.11.1
Gene ID: 11329
mRNA Refseq: NM_007271
Protein Refseq: NP_009202
MIM: 606964
UniProt ID: Q15208
Chromosome Location: 6p21
Function: ATP binding; magnesium ion binding; mitogen-activated protein kinase kinase kinase binding; nucleotide binding; protein binding; protein serine/threonine kinase activity

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