"CCL11" Related Products

Expand
Expand
Expand

Recombinant Human Chemokine (C-C motif) ligand 11,His-tagged

Cat. No. : CCL11-27H
Product Overview : Recombinant Human Eotaxin His Tag produced in E.Coli is a single, non-glycosylated polypeptide chain containing 74 amino acids fragment (24-87) corresponding to the mature Eotaxin protein and having a molecular mass of 8345.9 Dalton with an amino-terminal hexahistidine tag. The Eotaxin-His is purified by proprietary chromatographic techniques.
Description : Chemokine (C-C motif) ligand 11 (CCL11) is a small cytokine belonging to the CC chemokine family that is also known as eotaxin. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which CCL11 is a ligand include CCR2, CCR3 and CCR5. The gene for human CCL11 (scya11) is encoded on three exons and is located on chromosome 17.
Source : Escherichia Coli.
Physical Appearance : Sterile Filtered clear solution.
Purity : Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE
Formulation : Eotaxin-His is supplied in 1x PBS and 50% glycerol.
Storage : Lyophilized Eotaxin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL11 should be stored at 4°Cbetween 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Figure :

Gene Name : CCL11 chemokine (C-C motif) ligand 11 [ Homo sapiens ]
Synonyms : CCL11; chemokine (C-C motif) ligand 11; C-C motif chemokine 11; eotaxin; eotaxin-1; Eosinophil chemotactic protein; MGC22554; Small-inducible cytokine A11; small inducible cytokine A11; SCYA11; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
Gene ID : 6356
mRNA Refseq : NM_002986
Protein Refseq : NP_002977
MIM : 601156
UniProt ID : P51671
Chromosome Location : 17q21.1-q21.2
Pathway : Asthma; Chemokine signaling pathway; Cytokine-cytokine receptor interaction
Function : chemokine activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.