Native Human ACHE

PRODUCTS

Home / Products / Native Human ACHE

Native Human ACHE

ACHE Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : ACHE-8345H
Product Overview : Native Human ACHE was purified from Human erythrocytes.
Description : Acetylcholinesterase (AChE) is involved in cholinergic transmission, where it catalyses the hydrolysis of the neurotransmitter acetylcholine. A membrane-bound protein on the post-synaptic membrane. Also found in some non-neuronal cells, such as erythrocytes where its function is unclear. The erythrocyte enzyme extracted from the membrane anchor, using Triton-X 100, has a molecular weight 160,000. AChE is the target the organophosphorus insecticides such as parathion and malathion, all of which irreversibly inhibit the enzyme. Depressed levels of AChE activity is a sensitive indicator of exposure to these agents. It is also the target of anti-Alzheimer""s drrugs such as tacrine, which are reversible inhibitors of the enzyme. Raised levels of AChE in amniotic fluid are indicative of foetal neural tube defects.
Source : Human erythrocytes
Species : Human
Unit Definition : One unit will hydrolyse one micromole of Acetylthiocholine Iodide per minute at 37°C and pH 7.4.
Concentration : >450 U/mg
Gene Name : ACHE acetylcholinesterase [ Homo sapiens ]
Official Symbol : ACHE
Synonyms : ACHE; acetylcholinesterase; acetylcholinesterase (YT blood group) , acetylcholinesterase (Yt blood group) , YT; Yt blood group; apoptosis-related acetylcholinesterase; YT; ACEE; ARACHE; N-ACHE;
Gene ID : 43
mRNA Refseq : NM_000665
Protein Refseq : NP_000656
MIM : 100740
UniProt ID : P22303
Chromosome Location : 7q22
Pathway : ATF-2 transcription factor network, organism-specific biosystem; Acetylcholine Synthesis, organism-specific biosystem; Biogenic Amine Synthesis, organism-specific biosystem; Cholinergic synapse, organism-specific biosystem; Glycerophospholipid metabolism, organism-specific biosystem; Glycerophospholipid metabolism, conserved biosystem; Monoamine Transport, organism-specific biosystem;
Function : acetylcholine binding; acetylcholine binding; acetylcholinesterase activity; acetylcholinesterase activity; beta-amyloid binding; carboxylesterase activity; cholinesterase activity; collagen binding; hydrolase activity; laminin binding; protein binding; protein homodimerization activity; protein homodimerization activity; protein self-association; serine hydrolase activity;

Online Inquiry


  •  
  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved.