Recombinant Human CRLF1, GST-tagged CRLF1-311H

Recombinant Human CRLF1, GST-tagged

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Recombinant Human CRLF1, GST-tagged

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Cat.No. : CRLF1-311H
Product Overview : Recombinant Human CRLF1 encoding Human CRLF1 partial ORF ( NP_004741, 135 aa - 230 aa),fused with GST-tag at N-terminal, was expressed in Wheat germ.
Description : This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome.
Source : Wheat germ
Species : Human
Tag : GST
Molecular Mass : 36.3 kDa
AA Sequence : PEKPVNISCWSKNMK DLTCRWTPGAHGETF LHTNYSLKYKLRWYG QDNTCEEYHTVGPHS CHIPKDLALFTPYEI WVEATNRLGSARSDV LTLDIL
Applications : WB; ELISA
Storage : Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH8.0 in the elution buffer.
Figure :

Gene Name : CRLF1 cytokine receptor-like factor 1 [ Homo sapiens ]
Official Symbol : CRLF1
Synonyms : CRLF1; cytokine receptor-like factor 1; CISS; CISS1; CLF; CLF 1; cold induced sweating syndrome; cytokine-like factor 1; class I cytokine receptor; cytokine type 1 receptor CRLP-1; NR6; CLF-1; zcytor5;
Gene ID : 9244
mRNA Refseq : NM_004750
Protein Refseq : NP_004741
MIM : 604237
UniProt ID : O75462
Chromosome Location : 19p12
Function : contributes_to ciliary neurotrophic factor receptor binding; contributes_to cytokine activity; cytokine binding; protein binding; protein heterodimerization activity; receptor activity;

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