Recombinant Human CRLF1, GST-tagged

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Recombinant Human CRLF1, GST-tagged

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Cat.No. : CRLF1-319H
Product Overview : Recombinant Human CRLF1 encoding Human CRLF1 full-length ORF ( NP_004741.1, 1 aa - 422 aa),fused with GST-tag at N-terminal, was expressed in Wheat germ.
Description : This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome.
Source : Wheat germ
Species : Human
Tag : GST
Molecular Mass : 72.7 kDa
AA Sequence : MPAGRRGPAA QSARRPPPLL PLLLLLCVLG APRAGSGAHT AVISPQDPTL LIGSSLLATC SVHGDPPGAT AEGLYWTLNG RRLPPELSRV LNASTLALAL ANLNGSRQRS GDNLVCHARD GSILAGSCLY VGLPPEKPVN ISCWSKNMKD LTCRWTPGAH GETFLHTNYS LKYKLRWYGQ DNTCEEYHTV GPHSCHIPKD LALFTPYEIW VEATNRLGSA RSDVLTLDIL DVVTTDPPPD VHVSRVGGLE DQLSVRWVSP PALKDFLFQA KYQIRYRVED SVDWKVVDDV SNQTSCRLAG LKPGTVYFVQ VRCNPFGIYG SKKAGIWSEW SHPTAASTPR SERPGPGGGA CEPRGGEPSS GPVRRELKQF LGWLKKHAYC SNLSFRLYDQ WRAWMQKSHK TRNQDEGILP SGRRGTARGP AR
Applications : WB; ELISA
Storage : Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH8.0 in the elution buffer.
Figure :

Gene Name : CRLF1 cytokine receptor-like factor 1 [ Homo sapiens ]
Official Symbol : CRLF1
Synonyms : CRLF1; cytokine receptor-like factor 1; CISS; CISS1; CLF; CLF 1; cold induced sweating syndrome; cytokine-like factor 1; class I cytokine receptor; cytokine type 1 receptor CRLP-1; NR6; CLF-1; zcytor5;
Gene ID : 9244
mRNA Refseq : NM_004750
Protein Refseq : NP_004741
MIM : 604237
UniProt ID : O75462
Chromosome Location : 19p12
Function : contributes_to ciliary neurotrophic factor receptor binding; contributes_to cytokine activity; cytokine binding; protein binding; protein heterodimerization activity; receptor activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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