Active Recombinant Mouse Mrc1

• Cat.No.: Mrc1-12M
• Product Overview: Recombinant Mouse Mrc1(Leu19-Ala1388), fused with a C-terminal 6-His tag, was expressed in Mouse NSO Cells.

Specification

• Description: The Mannose Receptor (MR), a member of the vertebrate C-type lectin family, is a pattern recognition receptor that is involved in both innate and adaptive immunity.
• Source: Mammalian cells
• Species: Mouse
• Predicted N Terminal: Leu19
• Form: Lyophilized from a 0.2 μm filtered solution in PBS.
• Bio-activity: Measured by its ability to bind with Mannan in a functional ELISA.
• Molecular Mass: The recombinant Mouse Mrc1 predicts a molecular mass of 156 kDa (monomer). It migrates as an approximately 180 kDa band in SDS-PAGE under reducing conditions.
• Endotoxin: < 0.10 eu per 1 μg of the protein by the lal
• Purity: >90%, by SDS-PAGE
• Storage: Store it under sterile conditions at -20℃ to -70℃. It is recommended that the protein be aliquoted for optimal storage.
• Reconstitution: Reconstitute at 100 μg/mL in sterile PBS.

Gene Information

• Gene Name: MRC1 mannose receptor, C type 1 [ Homo sapiens ]
• Official Symbol: Mrc1
• Synonyms: MRC1; mannose receptor, C type 1; mannose receptor, C type 1 like 1 , MRC1L1; macrophage mannose receptor 1; bA541I19.1; CD206; CLEC13D; CLEC13DL; mannose receptor, C type 1-like 1; C-type lectin domain family 13 member D; macrophage mannose receptor 1-like protein 1; MMR; MRC1L1; MGC181940
• Gene ID: 4360
• mRNA Refseq: NM_002438
• Protein Refseq: NP_002429
• MIM: 153618
• UniProt ID: P22897
• Chromosome Location: 10p13
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Cross-presentation of soluble exogenous antigens (endosomes), organism-specific biosystem; Immune System, organism-specific biosystem; Phagosome, organism-specific biosystem
• Function: binding; mannose binding; receptor activity; sugar binding