Recombinant Porcine Interferon-gamma
Cat.No. : | IFNG-21P |
Product Overview : | Recombinant Porcine Interferon-gamma produced inE.Coliis a single, non-glycosylated, polypeptide chain containing 146 amino acids and having a molecular mass of 17140 Dalton. The IFN-gamma is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IFNG-21P |
Description : | IFN-gamma produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. |
Source : | E.Coli. |
Amino Acid Sequence : | The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Tyr-Cys-Gln-Ala. |
Physical Appearance : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Purity : | Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
Formulation : | The protein was lyophilized with no additives. |
Solubility : | It is recommended to reconstitute the lyophilized Interferon-gamma in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
Biological Activity : | The ED50as determined by theamount of interferon that inhibited 50% of the cytopathic effect of vesicular stomatitis virus in MDBK cells was < 0.3 ng/ml. |
Protein Content : | Protein quantitation was carried out by two independent methods: 1.UV spectroscopy at 280 nm using the absorbency value of 0.556 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a calibrated solution of IFN as a Reference Standard. |
Storage : | Lyophilized Interferon-g although stable at room temperature for 3 weeks, should be stored desiccated below -18℃. Upon reconstitution IFN gamma should be stored at 4℃ between 2-7 days and for future use below -18℃. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Gene Name : | IFNG interferon-gamma [ Sus scrofa ] |
Synonyms : | IFNG; Interferon-gamma; IFN-gamma Interferon gamma; Interferon, gamma; IFG; IFI; IFN-gamma; Immune interferon; Type II interferon; T cell interferon; MAF |
Gene ID : | 396991 |
mRNA Refseq : | NM_213948 |
Protein Refseq : | NP_999113 |
UniProt ID : | P17803 |
Chromosome Location : | 5p1.2-q1.1 |
Pathway : | Allograft rejection; Cytokine-cytokine receptor interaction; Graft-versus-host disease; Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity; Proteasome; Regulation of autophagy; Systemic lupus erythematosus; T cell receptor signaling pathway; TGF-beta signaling pathway; Type I diabetes mellitus |
Products Types
◆ Recombinant Protein | ||
IFNG-22H | Active Recombinant Human IFNG Protein | +Inquiry |
Ifng-031I | Active Recombinant Mouse Ifng Protein (134 aa) | +Inquiry |
Ifng-078M | Active Recombinant Mouse Ifng Protein | +Inquiry |
IFNG-198P | Active Recombinant Pig IFNG Protein (Gln23-Lys166), C-His tagged, Animal-free, Carrier-free | +Inquiry |
IFNG-116M | Active Recombinant Mouse IFNG Protein | +Inquiry |
◆ Lysates | ||
IFNG-1007FCL | Recombinant Ferret IFNG cell lysate | +Inquiry |
IFNG-1536RCL | Recombinant Rat IFNG cell lysate | +Inquiry |
IFNG-1797MCL | Recombinant Mouse IFNG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket