"ACTL7A" Related Products

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Recombinant Human ACTL7A, His-tagged

Cat.No.: ACTL7A-9336H
Product Overview: Recombinant Human ACTL7A protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.
Source: E.coli
Species: Human
Tag: His
Protein length: 1-280a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: ACTL7A actin-like 7A [ Homo sapiens ]
Official Symbol: ACTL7A
Synonyms: ACTL7A; actin-like 7A; actin-like protein 7A; actin-like 7-alpha; actin-like-7-alpha;
Gene ID: 10881
mRNA Refseq: NM_006687
Protein Refseq: NP_006678
MIM: 604303
UniProt ID: Q9Y615
Chromosome Location: 9q31
Function: structural constituent of cytoskeleton;

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