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Recombinant Human ACVR1C, GST-tagged

Cat.No. : ACVR1C-9356H
Product Overview : Recombinant Human ACVR1C protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
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Description : ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.
Source : E.coli
Species : Human
Tag : GST
Protein length : C-term-355a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : ACVR1C activin A receptor, type IC [ Homo sapiens ]
Official Symbol : ACVR1C
Synonyms : ACVR1C; activin A receptor, type IC; activin receptor type-1C; ACVRLK7; ALK7; ALK-7; ACTR-IC; activin receptor type IC; activin receptor-like kinase 7;
Gene ID : 130399
mRNA Refseq : NM_001111031
Protein Refseq : NP_001104501
MIM : 608981
UniProt ID : Q8NER5
Chromosome Location : 2q24.2
Pathway : Developmental Biology, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; Regulation of Signaling by NODAL, organism-specific biosystem; Signaling by NODAL, organism-specific biosystem; TGF-beta signaling pathway, organism-specific biosystem; TGF-beta signaling pathway, conserved biosystem;
Function : ATP binding; activin receptor activity, type I; metal ion binding; nucleotide binding; receptor activity; transforming growth factor beta-activated receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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