"AFF4" Related Products

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Recombinant Human AFF4, His-tagged

Cat.No.: AFF4-9457H
Product Overview: Recombinant Human AFF4 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23).
Source: E.coli
Species: Human
Tag: His
Protein length: 1-338a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: AFF4 AF4/FMR2 family, member 4 [ Homo sapiens ]
Official Symbol: AFF4
Synonyms: AFF4; AF4/FMR2 family, member 4; AF4/FMR2 family member 4; AF5Q31; ALL1 fused gene from 5q31; MCEF; ALL1-fused gene from chromosome 5q31 protein; major CDK9 elongation factor-associated protein; MGC75036;
Gene ID: 27125
mRNA Refseq: NM_014423
Protein Refseq: NP_055238
MIM: 604417
UniProt ID: Q9UHB7
Chromosome Location: 5q31
Function: protein binding; sequence-specific DNA binding transcription factor activity;

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