Recombinant Human AKAP7, GST-tagged

• Cat.No.: AKAP7-9524H
• Product Overview: Recombinant Human AKAP7 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-81a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: AKAP7 A kinase (PRKA) anchor protein 7 [ Homo sapiens ]
• Official Symbol: AKAP7
• Synonyms: AKAP7; A kinase (PRKA) anchor protein 7; A-kinase anchor protein 7 isoform gamma; AKAP15; AKAP18; AKAP 18; PRKA7 isoform gamma; AKAP-7 isoform gamma; PRKA7 isoforms alpha/beta; A-kinase anchor protein 9 kDa; A-kinase anchor protein 18 kDa; AKAP-7 isoforms alpha and beta; A-kinase anchor protein 7 isoforms alpha and beta
• Gene ID: 9465
• mRNA Refseq: NM_004842
• Protein Refseq: NP_004833
• MIM: 604693
• UniProt ID: O43687
• Chromosome Location: 6q22-q24
• Pathway: G Protein Signaling Pathways, organism-specific biosystem
• Function: AMP binding; catalytic activity; protein C-terminus binding; protein complex scaffold; protein domain specific binding; protein kinase A binding; protein kinase A binding; protein kinase A regulatory subunit binding; protein kinase binding