Recombinant Human ALDH5A1, His-tagged
Cat.No. : | ALDH5A1-9562H |
Product Overview : | Recombinant Human ALDH5A1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 175-535a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | ALDH5A1 aldehyde dehydrogenase 5 family, member A1 [ Homo sapiens ] |
Official Symbol : | ALDH5A1 |
Synonyms : | ALDH5A1; aldehyde dehydrogenase 5 family, member A1; succinate-semialdehyde dehydrogenase, mitochondrial; SSADH; SSDH; succinate semialdehyde dehydrogenase; aldehyde dehydrogenase family 5 member A1; mitochondrial succinate semialdehyde dehydrogenase; NAD(+)-dependent succinic semialdehyde dehydrogenase; |
Gene ID : | 7915 |
mRNA Refseq : | NM_001080 |
Protein Refseq : | NP_001071 |
MIM : | 610045 |
UniProt ID : | P51649 |
Chromosome Location : | 6p22 |
Pathway : | 4-aminobutyrate degradation I, organism-specific biosystem; 4-aminobutyrate degradation I, conserved biosystem; Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Butanoate metabolism, organism-specific biosystem; Butanoate metabolism, conserved biosystem; Degradation of GABA, organism-specific biosystem; |
Function : | oxidoreductase activity; protein homodimerization activity; succinate-semialdehyde dehydrogenase activity; succinate-semialdehyde dehydrogenase activity; |
Products Types
◆ Recombinant Protein | ||
ALDH5A1-1324H | Recombinant Human ALDH5A1 Protein (48-535 aa), His-tagged | +Inquiry |
ALDH5A1-2508H | Recombinant Human ALDH5A1 protein, His-SUMO-tagged | +Inquiry |
ALDH5A1-6188Z | Recombinant Zebrafish ALDH5A1 | +Inquiry |
ALDH5A1-450H | Recombinant Human ALDH5A1 Protein, GST-tagged | +Inquiry |
ALDH5A1-2821H | Recombinant Human ALDH5A1, His-tagged | +Inquiry |
◆ Lysates | ||
ALDH5A1-60HCL | Recombinant Human ALDH5A1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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