Recombinant Human ANAPC10, His-tagged
Cat.No. : | ANAPC10-9634H |
Product Overview : | Recombinant Human ANAPC10 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]). |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 1-185a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | ANAPC10 anaphase promoting complex subunit 10 [ Homo sapiens ] |
Official Symbol : | ANAPC10 |
Synonyms : | ANAPC10; anaphase promoting complex subunit 10; anaphase-promoting complex subunit 10; APC10; DKFZP564L0562; DOC1; cyclosome subunit 10; DKFZp564L0562; |
Gene ID : | 10393 |
mRNA Refseq : | NM_001256706 |
Protein Refseq : | NP_001243635 |
MIM : | 613745 |
UniProt ID : | Q9UM13 |
Chromosome Location : | 4q31 |
Pathway : | APC/C complex, organism-specific biosystem; APC/C complex, conserved biosystem; APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Cyclin B, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; |
Function : | ubiquitin-protein ligase activity; |
Products Types
◆ Recombinant Protein | ||
Anapc10-1619M | Recombinant Mouse Anapc10 Protein, Myc/DDK-tagged | +Inquiry |
ANAPC10-520M | Recombinant Mouse ANAPC10 Protein, His (Fc)-Avi-tagged | +Inquiry |
ANAPC10-337H | Recombinant Human ANAPC10 Protein, His (Fc)-Avi-tagged | +Inquiry |
ANAPC10-8244Z | Recombinant Zebrafish ANAPC10 | +Inquiry |
ANAPC10-4954H | Recombinant Human ANAPC10 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
ANAPC10-8871HCL | Recombinant Human ANAPC10 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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