Recombinant Human AP4B1, GST-tagged
Cat.No. : | AP4B1-9725H |
Product Overview : | Recombinant Human AP4B1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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- Gene Information
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Description : | This gene encodes a subunit of a heterotetrameric adapter-like complex 4 that is involved in targeting proteins from the trans-Golgi network to the endosomal-lysosomal system. Mutations in this gene are associated with cerebral palsy spastic quadriplegic type 5 (CPSQ5) disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-351a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | AP4B1 adaptor-related protein complex 4, beta 1 subunit [ Homo sapiens ] |
Official Symbol : | AP4B1 |
Synonyms : | AP4B1; adaptor-related protein complex 4, beta 1 subunit; spastic paraplegia 47 , SPG47; AP-4 complex subunit beta-1; beta 4 subunit of AP 4; BETA 4; beta4-adaptin; spastic paraplegia 47; beta 4 subunit of AP-4; CPSQ5; SPG47; BETA-4; |
Gene ID : | 10717 |
mRNA Refseq : | NM_001253852 |
Protein Refseq : | NP_001240781 |
MIM : | 607245 |
UniProt ID : | Q9Y6B7 |
Chromosome Location : | 1p13.2 |
Pathway : | Clathrin derived vesicle budding, organism-specific biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Membrane Trafficking, organism-specific biosystem; trans-Golgi Network Vesicle Budding, organism-specific biosystem; |
Function : | binding; protein transporter activity; transporter activity; |
Products Types
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AP4B1-661H | Recombinant Human AP4B1 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
AP4B1-8806HCL | Recombinant Human AP4B1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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