Recombinant Human ARHGAP2, His-tagged
Cat.No. : | ARHGAP26-9822H |
Product Overview : | Recombinant Human ARHGAP2His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 403--759a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | ARHGAP26 Rho GTPase activating protein 26 [ Homo sapiens ] |
Official Symbol : | ARHGAP26 |
Synonyms : | ARHGAP26; Rho GTPase activating protein 26; rho GTPase-activating protein 26; GRAF; GTPase regulator associated with the focal adhesion kinase pp125; KIAA0621; OPHN1L; OPHN1L1; oligophrenin-1-like protein; GTPase regulator associated with focal adhesion kinase pp125(FAK); GRAF1; FLJ42530; |
Gene ID : | 23092 |
mRNA Refseq : | NM_001135608 |
Protein Refseq : | NP_001129080 |
MIM : | 605370 |
UniProt ID : | Q9UNA1 |
Chromosome Location : | 5q31 |
Pathway : | Rho GTPase cycle, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by Rho GTPases, organism-specific biosystem; Signaling events mediated by focal adhesion kinase, organism-specific biosystem; |
Function : | GTPase activator activity; Rho GTPase activator activity; SH3 domain binding; cytoskeletal adaptor activity; protein binding; |
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◆ Lysates | ||
ARHGAP26-111HCL | Recombinant Human ARHGAP26 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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